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The practice of medicinal chemistry

Author: C G Wermuth
Publisher: Amsterdam ; Boston : Elsevier/Academic Press, 2008.
Edition/Format:   Print book : English : 3rd edView all editions and formats
Summary:
This title is directed towards organic chemists entering a career in drug research or in agrochemistry, and presents a complete guide to the drug discovery process.
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Genre/Form: Einführung
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: C G Wermuth
ISBN: 9780123741943 0123741947
OCLC Number: 262647294
Description: xxxvi, 942 pages : illustrations (some color), portraits (some color) ; 29 cm
Contents: Pt. 1: General aspects of medicial chemistry --
Pt. 2: Lead compound discovery strategies --
Pt. 3: Primary exploration of structure-activity relationships --
Pt. 4: Substituents and functions: qualitative and quantitative aspects of structure-activity relationships --
Pt. 5: Spatial organisation, receptor mapping and molecular modelling --
Pt. 6: Chemical modifications influencing pharmaceutical properties --
Pt. 7: Pharmaceutical and chemical means to solubility and formulation problems --
Pt. 8: Development of new drugs: legal and economic aspects.
Responsibility: edited by Camille Georges Wermuth.

Abstract:

Focuses on chemoinformatics and drug discovery. This book contains chapters including drug absorption and transport, and, multi-target drugs. It also tells how potential drugs can move through the  Read more...

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"Having favorably reviewed the first edition, I still highly recommend this third edition to all chemists who are involved in the drug discovery process."- John L. Neumeyer, Harvard Medical School, Read more...

 
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