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Principles of genetics

Author: D Peter Snustad; Michael J Simmons
Publisher: Hoboken, NJ : Wiley, ©2012.
Edition/Format:   Print book : English : 6th edView all editions and formats
Summary:
Snustad's 6th edition of Principles of Genetics offers many new and advanced features including boxed sections with the latest advances in Genetics, a streamlined roster of topics, a more reader-friendly layout, and new problem-solving supplements.
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Document Type: Book
All Authors / Contributors: D Peter Snustad; Michael J Simmons
ISBN: 9780470903599 0470903597
OCLC Number: 727356925
Notes: Includes index.
Description: xviii, 766 pages : illustrations (chiefly color) ; 29 cm
Contents: Machine generated contents note: ch. 1 The Science of Genetics --
The Personal Genome --
An Invitation --
Three Great Milestones in Genetics --
Mendel: Genes And The Rules Of Inheritance --
Watson And Crick: The Structure Of Dna --
The Human Genome Project: Sequencing Dna And Cataloguing Genes --
DNA as the Genetic Material --
Dna Replication: Propagating Genetic Information --
Gene Expression: Using Genetic Information --
Mutation: Changing Genetic Information --
Genetics and Evolution --
Levels of Genetic Analysis --
Classical Genetics --
Molecular Genetics --
Population Genetics --
Genetics in the World: Applications of Genetics to Human Endeavors --
Genetics In Agriculture --
Genetics In Medicine --
Genetics In Society --
ch. 2 Cellular Reproduction --
Dolly --
Cells and Chromosomes --
The Cellular Environment --
Prokaryotic And Eukaryotic Cells --
Chromosomes: Where Genes Are Located --
Cell Division --
Mitosis --
Meiosis --
Solve It How Much Dna In Human Meiotic Cells Note continued: Meiosis I --
Meiosis Ii And The Outcomes Of Meiosis --
Solve It How Many Chromosome Combinations In Sperm --
Life Cycles Of Some Model Genetic Organisms --
Saccharomyces Cerevisiae, Baker's Yeast --
Arabidopsis Thaliana, A Fast-Growing Plant --
Mus Musculus, The Mouse --
Problem-Solving Skills Counting Chromosomes And Chromatids --
ch. 3 Mendelism: The Basic Principles Of Inheritance --
The Birth Of Genetics: A Scientific Revolution --
Mendel's Study Of Heredity --
Mendel's Experimental Organism, The Garden Pea --
Monohybrid Crosses: The Principles Of Dominance And Segregation --
Dihybrid Crosses: The Principle Of Independent Assortment --
Applications Of Mendel's Principles --
The Punnett Square Method --
The Forked-Line Method --
The Probability Method --
Solve It Using Probabilities In A Genetic Problem --
Testing Genetic Hypotheses --
The Chi-Square Test --
Solve It Using The Chi-Square Test --
Mendelian Principles In Human Genetics --
Pedigrees Note continued: Mendelian Segregation In Human Families --
Genetic Counseling --
Problem-Solving Skills Making Predictions From Pedigrees --
ch. 4 Extensions Of Mendelism --
Genetics Grows Beyond Mendel's Monastery Garden --
Allelic Variation And Gene Function --
Incomplete Dominance And Codominance --
Multiple Alleles --
Allelic Series --
Testing Gene Mutations For Allelism --
Solve It The Test For Allelism --
Variation Among The Effects Of Mutations --
Genes Function To Produce Polypeptides --
Focus On Genetic Symbols --
Why Are Some Mutations Dominant And Others Recessive? --
Gene Action: From Genotype To Phenotype --
Influence Of The Environment --
Environmental Effects On The Expression Of Human Genes --
Penetrance And Expressivity --
Gene Interactions --
Epistasis --
Pleiotropy --
Problem-Solving Skills Going From Pathways To Phenotypic Ratios --
Inbreeding: Another Look At Pedigrees --
The Effects Of Inbreeding --
Genetic Analysis Of Inbreeding Note continued: Solve It Compound Inbreeding --
Measuring Genetic Relationships --
ch. 5 The Chromosomal Basis Of Mendelism --
Sex, Chromosomes, And Genes --
Chromosomes --
Chromosome Number --
Sex Chromosomes --
The Chromosome Theory Of Heredity --
Experimental Evidence Linking The Inheritance Of Genes To Chromosomes --
Nondisjunction As Proof Of The Chromosome Theory --
The Chromosomal Basis Of Mendel's Principles Of Segregation And Independent Assortment --
Solve It Sex Chromosome Nondisjunction --
Problem-Solving Skills Tracking X-Linked And Autosomal Inheritance --
Sex-Linked Genes In Humans --
Hemophilia, An X-Linked Blood-Clotting Disorder --
Color Blindness, An X-Linked Vision Disorder --
Genes On The Human Y Chromosome --
Solve It Calculating The Risk For Hemophilia --
Genes On Both The X And Y Chromosomes --
Sex Chromosomes And Sex Determination --
Sex Determination In Humans --
Sex Determination In Drosophila --
Sex Determination In Other Animals Note continued: Dosage Compensation Of X-Linked Genes --
Hyperactivation Of X-Linked Genes In Male Drosophila --
Inactivation Of X-Linked Genes In Female Mammals --
ch. 6 Variation In Chromosome Number And Structure --
Chromosomes, Agriculture, And Civilization --
Cytological Techniques --
Analysis Of Mitotic Chromosomes --
The Human Karyotype --
Cytogenetic Variation: An Overview --
Polyploidy --
Sterile Polyploids --
Fertile Polyploids --
Solve It Chromosome Pairing In Polyploids --
Tissue-Specific Polyploidy And Polyteny --
Aneuploidy --
Trisomy In Humans --
Monosomy --
Focus On Amniocentesis And Chorionic Biopsy --
Problem-Solving Skills Tracing Sex Chromosome Nondisjunction --
Deletions And Duplications Of Chromosome Segments --
Rearrangements Of Chromosome Structure --
Inversions --
Translocations --
Compound Chromosomes And Robertsonian Translocations --
Solve It Pollen Abortion In Translocation Heterozygotes Note continued: ch. 7 Linkage, Crossing Over, And Chromosome Mapping In Eukaryotes --
The World's First Chromosome Map --
Linkage, Recombination, And Crossing Over --
Early Evidence For Linkage And Recombination --
Crossing Over As The Physical Basis Of Recombination --
Evidence That Crossing Over Causes Recombination --
Chiasmata And The Time Of Crossing Over --
Chromosome Mapping --
Crossing Over As A Measure Of Genetic Distance --
Recombination Mapping With A Two-Point Testcross --
Recombination Mapping With A Three-Point Testcross --
Solve It Mapping Two Genes With Testcross Data --
Problem-Solving Skills Using A Genetic Map To Predict The Outcome Of A Cross --
Recombination Frequency And Genetic Map Distance --
Cytogenetic Mapping --
Localizing Genes Using Deletions And Duplications --
Genetic Distance And Physical Distance --
Solve It Cytological Mapping Of A Drosophila Gene --
Linkage Analysis In Humans --
Recombination And Evolution Note continued: Evolutionary Significance Of Recombination --
Suppression Of Recombination By Inversions --
Genetic Control Of Recombination --
ch. 8 The Genetics Of Bacteria And Their Viruses --
Multi-Drug-Resistant Bacteria: A Ticking Timebomb? --
Viruses And Bacteria In Genetics --
The Genetics Of Viruses --
Bacteriophage T4 --
Bacteriophage Lambda --
The Genetics Of Bacteria --
Mutant Genes In Bacteria --
Unidirectional Gene Transfer In Bacteria --
Mechanisms Of Genetic Exchange In Bacteria --
Transformation --
Conjugation --
Plasmids And Episomes --
Problem-Solving Skills Mapping Genes Using Conjugation Data --
F'Factors And Sexduction --
Transduction --
Solve It How Can You Map Closely Linked Genes Using Partial Diploids --
The Evolutionary Significance Of Genetic Exchange In Bacteria --
Solve It How Do Bacterial Genomes Evolve? --
On The Cutting Edge Antibiotic-Resistant Bacteria --
ch. 9 Dna And The Molecular Structure Of Chromosomes --
Discovery Of Nuclein Note continued: Functions Of The Genetic Material --
Proof That Genetic Information Is Stored In Dna --
Proof That Dna Mediates Transformation --
Proof That Dna Carries The Genetic Information In Bacteriophage T2 --
Proof That Rna Stores The Genetic Information In Some Viruses --
The Structures Of Dna And Rna --
Nature Of The Chemical Subunits In Dna And Rna --
Dna Structure: The Double Helix --
Problem-Solving Skills Calculating Base Content In Dna --
Dna Structure: Alternate Forms Of The Double Helix --
Solve It What Are Some Important Features Of Double-Stranded Dna? --
Dna Structure: Negative Supercoils In Vivo --
Chromosome Structure In Prokaryotes And Viruses --
Chromosome Structure In Eukaryotes --
Chemical Composition Of Eukaryotic Chromosomes --
One Large Dna Molecule Per Chromosome --
Three Levels Of Dna Packaging In Eukaryotic Chromosomes --
Solve It How Many Nucleosomes In One Human X Chromosome --
Centromeres And Telomeres --
Repeated Dna Sequences Note continued: On The Cutting Edge The 1000 Genomes Project --
ch. 10 Replication Of Dna And Chromosomes --
Monozygotic Twins: Are They Identical? --
Basic Features Of Dna Replication In Vivo --
Semiconservative Replication --
Solve It Understanding The Semiconservative Replication Of Dna --
Unique Origins Of Replication --
Problem-Solving Skills Predicting Patterns Of 3H Labeling In Chromosomes --
Visualization Of Replication Forks By Autoradiography --
Bidirectional Replication --
Dna Replication In Prokaryotes --
Focus On Dna Synthesis In Vitro --
Continuous Synthesis Of One Strand; Discontinuous Synthesis Of The Other Strand --
Covalent Closure Of Nicks In Dna By Dna Ligase --
Initiation Of Dna Replication --
Initiation Of Dna Chains With Rna Primers --
Unwinding Dna With Helicases, Dna-Binding Proteins, And Topoisomerases --
Multiple Dna Polymerases And Proofreading --
The Primosome And The Replisome --
Rolling-Circle Replication Note continued: Unique Aspects Of Eukaryotic Chromosome Replication --
The Cell Cycle --
Multiple Replicons Per Chromosome --
Solve It Understanding Replication Of The Human X Chromosome --
Two Or More Dna Polymerases At A Single Replication Fork --
Duplication Of Nucleosomes At Replication Forks --
Telomerase: Replication Of Chromosome Termini --
Telomere Length And Aging In Humans --
ch. 11 Transcription And Rna Processing --
Storage And Transmission Of Information With Simple Codes --
Transfer Of Genetic Information: The Central Dogma --
Transcription And Translation --
Five Types Of Rna Molecules --
The Process Of Gene Expression --
An Mrna Intermediary --
General Features Of Rna Synthesis --
Problem-Solving Skills Distinguishing Rnas Transcribed From Viral And Host Dnas --
Transcription In Prokaryotes --
Rna Polymerases: Complex Enzymes --
Initiation Of Rna Chains --
Elongation Of Rna Chains --
Termination Of Rna Chains Note continued: Concurrent Transcription, Translation, And Mrna Degradation --
Transcription And Rna Processing In Eukaryotes --
Five Rna Polymerases/Five Sets Of Genes --
On The Cutting Edge Chromatin Remodeling And Gene Expression --
Initiation Of Rna Chains --
Solve It Initiation Of Transcription By Rna Polymerase Ii In Eukaryotes --
Rna Chain Elongation And The Addition Of 5' Methyl Guanosine Caps --
Termination By Chain Cleavage And The Addition Of 3' Poly(A) Tails --
Solve It Formation Of The 3'-Terminus Of An Rna Polymerase Ii Transcript --
Rna Editing: Altering The Information Content Of Mrna Molecules --
Interrupted Genes In Eukaryotes: Exons And Introns --
Some Very Large Eukaryotic Genes --
Introns: Biological Significance? --
Removal Of Intron Sequences By Rna Splicing --
TRna Precursor Splicing: Unique Nuclease And Ligase Activities --
Autocatalytic Splicing --
Pre-Mrna Splicing: Snrnas, Snrnps, And The Spliceosome Note continued: ch. 12 Translation And The Genetic Code --
Sickle-Cell Anemia: Devastating Effects Of A Single Base-Pair Change --
Protein Structure --
Polypeptides: Twenty Different Amino Acid Subunits --
Proteins: Complex Three-Dimensional Structures --
One Gene --
One Colinear Polypeptide --
Beadle And Tatum: One Gene --
One Enzyme --
Colinearity Beween The Coding Sequence Of A Gene And Its Polypeptide Product --
Protein Synthesis: Translation --
Overview Of Protein Synthesis --
Components Required For Protein Synthesis: Ribosomes --
Components Required For Protein Synthesis: Transfer Rnas --
Translation: The Synthesis Of Polypeptides Using Mrna Templates --
Solve It Control Of Translation In Eukaryotes --
The Genetic Code --
Properties Of The Genetic Code: An Overview --
Three Nucleotides Per Codon --
Deciphering The Code --
Initiation And Termination Codons --
A Degenerate And Ordered Code Note continued: Problem-Solving Skills Predicting Amino Acid Substitutions Induced By Mutagens --
A Nearly Universal Code --
Codon-Trna Interactions --
Recognition Of Codons By Trnas: The Wobble Hypothesis --
Suppressor Mutations That Produce Trnas With Altered Codon Recognition --
Solve It Effects Of Base-Pair Substitutions In The Coding Region Of The Hbb Gene --
On The Cutting Edge Selenocysteine, The 21St Amino Acid --
ch. 13 Mutation, Dna Repair, And Recombination --
Xeroderma Pigmentosum: Defective Repair Of Damaged Dna In Humans --
Mutation: Source Of The Genetic Variability Required For Evolution --
The Molecular Basis Of Mutation --
Solve It Nucleotide-Pair Substitutions In The Human Hbb Gene --
Induced Mutations --
Mutations Induced By Chemicals --
Mutations Induced By Radiation --
Problem-Solving Skills Predicting Amino Acid Changes Induced By Chemical Mutagens --
Mutations Induced By Transposable Genetic Elements Note continued: Expanding Trinucleotide Repeats And Inherited Human Diseases --
Mutation: Basic Features Of The Process --
Mutation: Somatic Or Germinal --
Mutation: Spontaneous Or Induced --
Mutation: Usually A Random, Nonadaptive Process --
Mutation: A Reversible Process --
Mutation: Phenotypic Effects --
Mutations With Phenotypic Efects: Usually Deleterious And Recessive --
Effects Of Mutations In Human Globin Genes --
Mutation In Humans: Blocks In Metabolic Pathways --
On The Cutting Edge Screening Eight-Cell Pre-Embryos For Tay-Sachs Muitations --
Conditional Lethal Mutations: Powerful Tools For Genetic Studies --
Assigning Mutations To Genes By The Complementation Test --
Solve It How Can You Assign Mutations To Genes? --
Screening Chemicals For Mutagenicity: The Ames Test --
Dna Repair Mechanisms --
Light-Dependent Repair --
Excision Repair --
Other Dna Repair Mechanisms --
Inherited Human Diseases With Defects In Dna Repair --
Dna Recombination Mechanisms Note continued: Recombination: Cleavage And Rejoining Of Dna Molecules --
Gene Conversion: Dna Repair Synthesis Associated With Recombination --
ch. 14 The Techniques Of Molecular Genetics --
Treatment Of Pituitary Dwarfism With Human Growth Hormone --
Basic Techniques Used To Identify, Amplify, And Clone Genes --
Solve It How Many Not! Restriction Fragments In Chimpanzee Dna? --
The Discovery Of Restriction Endonucleases --
The Production Of Recombinant Dna Molecules In Vitro --
Amplification Of Recombinant Dna Molecules In Cloning Vectors --
Cloning Large Genes And Segments Of Genomes In Bacs, Pacs, And Yacs --
Amplification Of Dna Sequences By The Polymerase Chain Reaction (Pcr) --
Construction And Screening Of Dna Libraries --
Construction Of Genomic Libraries --
Construction Of Cdna Libraries --
Screening Dna Libraries For Genes Of Interest --
Solve It How Can You Clone A Specific Not! Restriction Fragment From The Orangutan Genome? Note continued: The Molecular Analysis Of Dna, Rna, And Protein --
Analysis Of Dnas By Southern Blot Hybridizations --
Analysis Of Rnas By Northern Blot Hybridizations --
Focus On Detection Of A Mutant Gene Causing Cystic Fibrosis --
Analysis Of Rnas By Reverse Transriptase-Pcr (Rt-Pcr) --
Analysis Of Proteins By Western Blot Techniques --
The Molecular Analysis Of Genes And Chromosomes --
Physical Maps Of Dna Molecules Based On Restriction Enzyme Cleavage Sites --
Nucleotide Sequences Of Genes And Chromosomes --
Problem-Solving Skills Determining The Nucleotide Sequences Of Genetic Elements --
ch. 15 Genomics --
The Neanderthal Genome: What It Reveals About Our Ancestors --
Focus On Genbank --
Genomics: An Overview --
Correlated Genetic, Cytological, And Physical Maps Of Chromosomes --
Restriction Fragment-Length Polymorphism (Rflp) And Short Tandem Repeat (Str) Maps --
Cytogenetic Maps --
Physical Maps And Clone Banks --
Map Position-Based Cloning Of Genes Note continued: Chromosome Walks And Jumps --
The Human Genome Project --
Mapping The Human Genome --
Sequencing The Human Genome --
The Human Hapmap Project --
Rna And Protein Assays Of Genome Function --
Expressed Sequences --
Microarrays And Gene Chips --
The Green Fluorescent Protein As A Reporter Of Protein Synthesis --
Comparative Genomics --
Bioinformatics --
Problem-Solving Skills Using Bioinformatics To Investigate Dna Sequences --
Prokaryotic Genomes --
A Living Bacterium With A Chemically Synthesized Genome --
The Genomes Of Chloroplasts And Mitochondria --
Solve It What Do We Know About The Mitochondrial Genome Of The Extinct Woolly Mammoth? --
Eukaryotic Genomes --
Solve It What Can You Learn About Dna Sequences Using Bioinformatics? --
Genome Evolution In The Cereal Grasses --
Genome Evolution In Mammals --
ch. 16 Applications Of Molecular Genetics --
Gene Therapy Improves Sight In Child With Congenital Blindness Note continued: Use Of Recombinant Dna Technology To Identify Human Genes And Diagnose Human Diseases --
Huntington's Disease --
Focus On Fragile X Syndrome And Expanded Trinucleotide Repeats --
Problem-Solving Skills Testing For Mutant Alleles That Cause Fragile X Mental Retardation --
Cystic Fibrosis --
Molecular Diagnosis Of Human Diseases --
Human Gene Therapy --
Dna Profiling --
Paternity Tests --
Solve It How Can Dna Profiles Be Used To Establish Identity? --
Forensic Applications --
Production Of Eukaryotic Proteins In Bacteria --
Human Growth Hormone --
Proteins With Industrial Applications --
Transgenic Plants And Animals --
Transgenic Animals: Microinjection Of Dna Into Fertilized Eggs And Transfection Of Embryonic Stem Cells --
Transgenic Plants: The T1 Plasmid Of Agrobacterium Tumefaciens --
Reverse Genetics: Dissecting Biological Processes By Inhibiting Gene Expression --
Knockout Mutations In The Mouse --
T-Dna And Transposon Insertions Note continued: Rna Interference --
Solve It How Might Rna Interference Be Used To Treat Burkitt's Lymphoma? --
ch. 17 Transposable Genetic Elements --
Maize: A Staple Crop With A Cultural Heritage --
Transposable Elements: An Overview --
Transposable Elements In Bacteria --
Is Elements --
Solve It Accumulating Drug-Resistance Genes --
Composite Transposons --
The Tn3 Element --
Cut-And-Paste Transposons In Eukaryotes --
Ac And Ds Elements In Maize --
P Elements And Hybrid Dysgenesis In Drosophila --
Problem-Solving Skills Analyzing Transposon Activity In Maize --
On The Cutting Edge Small Rnas Repress P Element Activity --
Retroviruses And Retrotransposons --
Retroviruses --
Retroviruslike Elements --
Retroposons --
Transposable Elements In Humans --
The Genetic And Evolutionary Significance Of Transposable Elements --
Transposons As Mutagens --
Genetic Transformation With Transposons --
Solve It Transposon-Mediated Chromosome Rearrangements Note continued: Transposons And Genome Organization --
ch. 18 Regulation Of Gene Expression In Prokaryotes --
D'Herelle's Dream Of Treating Dysentery In Humans By Phage Therapy --
Constitutive, Inducible, And Repressible Gene Expression --
Positive And Negative Control Of Gene Expression --
Operons: Coordinately Regulated Units Of Gene Expression --
The Lactose Operon In E. Coli: Induction And Catabolite Repression --
Induction --
Solve It Constitutive Mutations In The E. Coli Lac Operon --
Catabolite Repression --
Problem Solving Skills Testing Your Understanding Of The Lac Operon --
Protein-Dna Interactions That Control Transcription Of The Lac Operon --
The Tryptophan Operon In E. Coli: Repression And Attenuation --
Repression --
Attenuation --
Solve It Regulation Of The Histidine Operon Of Salmonella Typhimurium --
On The Cutting Edge The Lysine Riboswitch --
Translational Control Of Gene Expression --
Posttranslational Regulatory Mechanisms Note continued: ch. 19 Regulation Of Gene Expression In Eukaryotes --
African Trypanosomes: A Wardrobe Of Molecular Disguises --
Ways Of Regulating Eukaryotic Gene Expression: An Overview --
Dimensions Of Eukaryotic Gene Regulation --
Controlled Transcription Of Dna --
Alternate Splicing Of Rna --
Solve It Counting Mrnas --
Cytoplasmic Control Of Messenger Rna Stability --
Induction Of Transcriptional Activity By Environmental And Biological Factors --
Temperature: The Heat-Shock Genes --
Signal Molecules: Genes That Respond To Hormones --
Molecular Control Of Transcription In Eukaryotes --
Dna Sequences Involved In The Control Of Transcription --
Proteins Involved In The Control Of Transcription: Transcription Factors --
Problem-Solving Skills Defining The Sequences Required For A Gene's Expression --
Posttranscriptional Regulation Of Gene Expression By Rna Interference --
Rnai Pathways --
Sources Of Short Interfering Rnas And Micrornas Note continued: Gene Expression And Chromatin Organization --
Solve It Using Rnai In Cell Research --
Euchromatin And Heterochromatin --
Molecular Organization Of Transcriptionally Active Dna --
Chromatin Remodeling --
Dna Methylation --
Imprinting --
On The Cutting Edge The Epigenetics Of Twins --
Activation And Inactivation Of Whole Chromosomes --
Inactivation Of X Chromosomes In Mammals --
Hyperactivation Of X Chromosomes In Drosophila --
Hypoactivation Of X Chromosomes In Caenorhabditis --
ch. 20 The Genetic Control Of Animal Development --
Stem-Cell Therapy --
A Genetic Perspective On Development --
Maternal Gene Activity In Development --
Maternal-Effect Genes --
Solve It A Maternal-Effect Mutation In The Cinnamon Gene --
Determination Of The Dorsal-Ventral And Anterior-Posterior Axes --
Zygotic Gene Activity In Development --
Body Segmentation --
Organ Formation --
Specification Of Cell Types --
Solve It Cave Blindness Note continued: Problem-Solving Skills The Effects Of Mutations During Eye Development --
Genetic Analysis Of Development In Vertebrates --
Vertebrate Homologues Of Invertebrate Genes --
The Mouse: Random Insertion Mutations And Gene-Specific Knockout Mutations --
Studies With Mammalian Stem Cells --
Reproductive Cloning --
Genetic Changes In The Differentiation Of Vertebrate Immune Cells --
ch. 21 The Genetic Basis Of Cancer --
A Molecular Family Connection --
Cancer: A Genetic Disease --
The Many Forms Of Cancer --
Cancer And The Cell Cycle --
Cancer And Programmed Cell Death --
A Genetic Basis For Cancer --
Oncogenes --
Tumor-Inducing Retroviruses And Viral Oncogenes --
Solve It The V-Erbb And V-Fms Viral Oncogenes --
Cellular Homologues Of Viral Oncogenes: The Proto-Oncogenes --
Mutant Cellular Oncogenes And Cancer --
Chromosome Rearrangements And Cancer --
Tumor Suppressor Genes --
Inherited Cancers And Knudson's Two-Hit Hypothesis Note continued: Problem-Solving Skills Estimating Mutation Rates In Retinoblastoma --
Cellular Roles Of Tumor Suppressor Proteins --
Prb --
P53 --
Solve It Downstream Of P53 --
Papc --
Phmsh2 --
Pbrca1 And Pbrca2 --
Focus On Cancer And Genetic Counseling --
Genetic Pathways To Cancer --
ch. 22 Inheritance Of Complex Traits --
Cardiovascular Disease: A Combination Of Genetic And Environmental Factors --
Complex Traits --
Quantifying Complex Traits --
Genetic And Environmental Factors Influence Quantitative Traits --
Multiple Genes Influence Quantitative Traits --
Threshold Traits --
Statistics Of Quantitative Genetics --
Frequency Distributions --
The Mean And The Modal Class --
The Variance And The Standard Deviation --
Analysis Of Quantitative Traits --
The Multiple Factor Hypothesis --
Partitioning The Phenotypic Variance --
Solve It Estimating Genetic And Environmental Variance Components --
Broad-Sense Heritability --
Narrow-Sense Heritability Note continued: Predicting Phenotypes --
Solve It Using The Narrow-Sense Heritability --
Artificial Selection --
Focus On Artificial Selection --
Quantitative Trait Loci --
Problem-Solving Skills Detecting Dominance At A Qtl --
Correlations Between Relatives --
Correlating Quantitative Phenotypes Between Relatives --
Interpreting Correlations Between Relatives --
Quantitative Genetics Of Human Behavioral Traits --
Intelligence --
Personality --
ch. 23 Population Genetics --
A Remote Colony --
The Theory Of Allele Frequencies --
Estimating Allele Frequencies --
Relating Genotype Frequencies To Allele Frequencies: The Hardy-Weinberg Principle --
Applications Of The Hardy-Weinberg Principle --
Exceptions To The Hardy-Weinberg Principle --
Solve It The Effects Of Inbreeding On Hardy-Weinberg Frequencies --
Using Allele Frequencies In Genetic Counseling --
Natural Selection --
The Concept Of Fitness --
Natural Selection At The Level Of The Gene Note continued: Solve It Selection Against A Harmful Recessive Allele --
Random Genetic Drift --
Random Changes In Allele Frequencies --
The Effects Of Population Size --
Problem-Solving Skills Applying Genetic Drift To Pitcairn Island --
Populations In Genetic Equilibrium --
Balancing Selection --
Mutation-Selection Balance --
Mutation-Drift Balance --
ch. 24 Evolutionary Genetics --
D'Ou Venons Nous? Que Sommes Nous? Ou Allons Nous? --
The Emergence Of Evolutionary Theory --
Darwin's Theory Of Evolution --
Evolutionary Genetics --
Genetic Variation In Natural Populations --
Variation In Phenotypes --
Variation In Chromosome Structure --
Variation In Protein Structure --
Variation In Nucleotide Sequences --
Molecular Evolution --
Molecules As "Documents Of Evolutionary History" --
Molecular Phylogenies --
Rates Of Molecular Evolution --
Problem-Solving Skills Using Mitochondrial Dna To Establish A Phylogeny --
The Molecular Clock Note continued: Solve It Calculating Divergence Times --
Variation In The Evolution Of Protein Sequences --
Variation In The Evolution Of Dna Sequences --
The Neutral Theory Of Molecular Evolution --
Solve It Evolution By Mutation And Genetic Drift --
Molecular Evolution And Phenotypic Evolution --
Speciation --
What Is A Species? --
Modes Of Speciation --
Human Evolution --
Humans And The Great Apes --
Human Evolution In The Fossil Record --
Dna Sequence Variation And Human Origins --
Appendices --
Appendix A The Rules Of Probability --
Appendix B Binomial Probabilities --
Appendix C : In Situ Hybridization --
Appendix D Evidence For An Unstable Messenger Rna --
Appendix E Evolutionary Rates.
Responsibility: D. Peter Snustad, Michael J. Simmons.

Abstract:

Snustad's 6th edition of Principles of Genetics offers many new and advanced features including boxed sections with the latest advances in Genetics, a streamlined roster of topics, a more reader-friendly layout, and new problem-solving supplements.

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   library:placeOfPublication <http://id.loc.gov/vocabulary/countries/nju> ;
   schema:about <http://id.worldcat.org/fast/940117> ; # Genetics
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   schema:creator <http://viaf.org/viaf/9923161> ; # D Peter Snustad
   schema:datePublished "2012" ;
   schema:description "Note continued: Transposons And Genome Organization -- ch. 18 Regulation Of Gene Expression In Prokaryotes -- D'Herelle's Dream Of Treating Dysentery In Humans By Phage Therapy -- Constitutive, Inducible, And Repressible Gene Expression -- Positive And Negative Control Of Gene Expression -- Operons: Coordinately Regulated Units Of Gene Expression -- The Lactose Operon In E. Coli: Induction And Catabolite Repression -- Induction -- Solve It Constitutive Mutations In The E. Coli Lac Operon -- Catabolite Repression -- Problem Solving Skills Testing Your Understanding Of The Lac Operon -- Protein-Dna Interactions That Control Transcription Of The Lac Operon -- The Tryptophan Operon In E. Coli: Repression And Attenuation -- Repression -- Attenuation -- Solve It Regulation Of The Histidine Operon Of Salmonella Typhimurium -- On The Cutting Edge The Lysine Riboswitch -- Translational Control Of Gene Expression -- Posttranslational Regulatory Mechanisms"@en ;
   schema:description "Note continued: Recombination: Cleavage And Rejoining Of Dna Molecules -- Gene Conversion: Dna Repair Synthesis Associated With Recombination -- ch. 14 The Techniques Of Molecular Genetics -- Treatment Of Pituitary Dwarfism With Human Growth Hormone -- Basic Techniques Used To Identify, Amplify, And Clone Genes -- Solve It How Many Not! Restriction Fragments In Chimpanzee Dna? -- The Discovery Of Restriction Endonucleases -- The Production Of Recombinant Dna Molecules In Vitro -- Amplification Of Recombinant Dna Molecules In Cloning Vectors -- Cloning Large Genes And Segments Of Genomes In Bacs, Pacs, And Yacs -- Amplification Of Dna Sequences By The Polymerase Chain Reaction (Pcr) -- Construction And Screening Of Dna Libraries -- Construction Of Genomic Libraries -- Construction Of Cdna Libraries -- Screening Dna Libraries For Genes Of Interest -- Solve It How Can You Clone A Specific Not! Restriction Fragment From The Orangutan Genome?"@en ;
   schema:description "Note continued: Problem-Solving Skills Estimating Mutation Rates In Retinoblastoma -- Cellular Roles Of Tumor Suppressor Proteins -- Prb -- P53 -- Solve It Downstream Of P53 -- Papc -- Phmsh2 -- Pbrca1 And Pbrca2 -- Focus On Cancer And Genetic Counseling -- Genetic Pathways To Cancer -- ch. 22 Inheritance Of Complex Traits -- Cardiovascular Disease: A Combination Of Genetic And Environmental Factors -- Complex Traits -- Quantifying Complex Traits -- Genetic And Environmental Factors Influence Quantitative Traits -- Multiple Genes Influence Quantitative Traits -- Threshold Traits -- Statistics Of Quantitative Genetics -- Frequency Distributions -- The Mean And The Modal Class -- The Variance And The Standard Deviation -- Analysis Of Quantitative Traits -- The Multiple Factor Hypothesis -- Partitioning The Phenotypic Variance -- Solve It Estimating Genetic And Environmental Variance Components -- Broad-Sense Heritability -- Narrow-Sense Heritability"@en ;
   schema:description "Note continued: The Molecular Analysis Of Dna, Rna, And Protein -- Analysis Of Dnas By Southern Blot Hybridizations -- Analysis Of Rnas By Northern Blot Hybridizations -- Focus On Detection Of A Mutant Gene Causing Cystic Fibrosis -- Analysis Of Rnas By Reverse Transriptase-Pcr (Rt-Pcr) -- Analysis Of Proteins By Western Blot Techniques -- The Molecular Analysis Of Genes And Chromosomes -- Physical Maps Of Dna Molecules Based On Restriction Enzyme Cleavage Sites -- Nucleotide Sequences Of Genes And Chromosomes -- Problem-Solving Skills Determining The Nucleotide Sequences Of Genetic Elements -- ch. 15 Genomics -- The Neanderthal Genome: What It Reveals About Our Ancestors -- Focus On Genbank -- Genomics: An Overview -- Correlated Genetic, Cytological, And Physical Maps Of Chromosomes -- Restriction Fragment-Length Polymorphism (Rflp) And Short Tandem Repeat (Str) Maps -- Cytogenetic Maps -- Physical Maps And Clone Banks -- Map Position-Based Cloning Of Genes"@en ;
   schema:description "Note continued: Solve It Compound Inbreeding -- Measuring Genetic Relationships -- ch. 5 The Chromosomal Basis Of Mendelism -- Sex, Chromosomes, And Genes -- Chromosomes -- Chromosome Number -- Sex Chromosomes -- The Chromosome Theory Of Heredity -- Experimental Evidence Linking The Inheritance Of Genes To Chromosomes -- Nondisjunction As Proof Of The Chromosome Theory -- The Chromosomal Basis Of Mendel's Principles Of Segregation And Independent Assortment -- Solve It Sex Chromosome Nondisjunction -- Problem-Solving Skills Tracking X-Linked And Autosomal Inheritance -- Sex-Linked Genes In Humans -- Hemophilia, An X-Linked Blood-Clotting Disorder -- Color Blindness, An X-Linked Vision Disorder -- Genes On The Human Y Chromosome -- Solve It Calculating The Risk For Hemophilia -- Genes On Both The X And Y Chromosomes -- Sex Chromosomes And Sex Determination -- Sex Determination In Humans -- Sex Determination In Drosophila -- Sex Determination In Other Animals"@en ;
   schema:description "Note continued: ch. 12 Translation And The Genetic Code -- Sickle-Cell Anemia: Devastating Effects Of A Single Base-Pair Change -- Protein Structure -- Polypeptides: Twenty Different Amino Acid Subunits -- Proteins: Complex Three-Dimensional Structures -- One Gene -- One Colinear Polypeptide -- Beadle And Tatum: One Gene -- One Enzyme -- Colinearity Beween The Coding Sequence Of A Gene And Its Polypeptide Product -- Protein Synthesis: Translation -- Overview Of Protein Synthesis -- Components Required For Protein Synthesis: Ribosomes -- Components Required For Protein Synthesis: Transfer Rnas -- Translation: The Synthesis Of Polypeptides Using Mrna Templates -- Solve It Control Of Translation In Eukaryotes -- The Genetic Code -- Properties Of The Genetic Code: An Overview -- Three Nucleotides Per Codon -- Deciphering The Code -- Initiation And Termination Codons -- A Degenerate And Ordered Code"@en ;
   schema:description "Note continued: On The Cutting Edge The 1000 Genomes Project -- ch. 10 Replication Of Dna And Chromosomes -- Monozygotic Twins: Are They Identical? -- Basic Features Of Dna Replication In Vivo -- Semiconservative Replication -- Solve It Understanding The Semiconservative Replication Of Dna -- Unique Origins Of Replication -- Problem-Solving Skills Predicting Patterns Of 3H Labeling In Chromosomes -- Visualization Of Replication Forks By Autoradiography -- Bidirectional Replication -- Dna Replication In Prokaryotes -- Focus On Dna Synthesis In Vitro -- Continuous Synthesis Of One Strand; Discontinuous Synthesis Of The Other Strand -- Covalent Closure Of Nicks In Dna By Dna Ligase -- Initiation Of Dna Replication -- Initiation Of Dna Chains With Rna Primers -- Unwinding Dna With Helicases, Dna-Binding Proteins, And Topoisomerases -- Multiple Dna Polymerases And Proofreading -- The Primosome And The Replisome -- Rolling-Circle Replication"@en ;
   schema:description "Note continued: Dosage Compensation Of X-Linked Genes -- Hyperactivation Of X-Linked Genes In Male Drosophila -- Inactivation Of X-Linked Genes In Female Mammals -- ch. 6 Variation In Chromosome Number And Structure -- Chromosomes, Agriculture, And Civilization -- Cytological Techniques -- Analysis Of Mitotic Chromosomes -- The Human Karyotype -- Cytogenetic Variation: An Overview -- Polyploidy -- Sterile Polyploids -- Fertile Polyploids -- Solve It Chromosome Pairing In Polyploids -- Tissue-Specific Polyploidy And Polyteny -- Aneuploidy -- Trisomy In Humans -- Monosomy -- Focus On Amniocentesis And Chorionic Biopsy -- Problem-Solving Skills Tracing Sex Chromosome Nondisjunction -- Deletions And Duplications Of Chromosome Segments -- Rearrangements Of Chromosome Structure -- Inversions -- Translocations -- Compound Chromosomes And Robertsonian Translocations -- Solve It Pollen Abortion In Translocation Heterozygotes"@en ;
   schema:description "Note continued: Predicting Phenotypes -- Solve It Using The Narrow-Sense Heritability -- Artificial Selection -- Focus On Artificial Selection -- Quantitative Trait Loci -- Problem-Solving Skills Detecting Dominance At A Qtl -- Correlations Between Relatives -- Correlating Quantitative Phenotypes Between Relatives -- Interpreting Correlations Between Relatives -- Quantitative Genetics Of Human Behavioral Traits -- Intelligence -- Personality -- ch. 23 Population Genetics -- A Remote Colony -- The Theory Of Allele Frequencies -- Estimating Allele Frequencies -- Relating Genotype Frequencies To Allele Frequencies: The Hardy-Weinberg Principle -- Applications Of The Hardy-Weinberg Principle -- Exceptions To The Hardy-Weinberg Principle -- Solve It The Effects Of Inbreeding On Hardy-Weinberg Frequencies -- Using Allele Frequencies In Genetic Counseling -- Natural Selection -- The Concept Of Fitness -- Natural Selection At The Level Of The Gene"@en ;
   schema:description "Note continued: Expanding Trinucleotide Repeats And Inherited Human Diseases -- Mutation: Basic Features Of The Process -- Mutation: Somatic Or Germinal -- Mutation: Spontaneous Or Induced -- Mutation: Usually A Random, Nonadaptive Process -- Mutation: A Reversible Process -- Mutation: Phenotypic Effects -- Mutations With Phenotypic Efects: Usually Deleterious And Recessive -- Effects Of Mutations In Human Globin Genes -- Mutation In Humans: Blocks In Metabolic Pathways -- On The Cutting Edge Screening Eight-Cell Pre-Embryos For Tay-Sachs Muitations -- Conditional Lethal Mutations: Powerful Tools For Genetic Studies -- Assigning Mutations To Genes By The Complementation Test -- Solve It How Can You Assign Mutations To Genes? -- Screening Chemicals For Mutagenicity: The Ames Test -- Dna Repair Mechanisms -- Light-Dependent Repair -- Excision Repair -- Other Dna Repair Mechanisms -- Inherited Human Diseases With Defects In Dna Repair -- Dna Recombination Mechanisms"@en ;
   schema:description "Note continued: Mendelian Segregation In Human Families -- Genetic Counseling -- Problem-Solving Skills Making Predictions From Pedigrees -- ch. 4 Extensions Of Mendelism -- Genetics Grows Beyond Mendel's Monastery Garden -- Allelic Variation And Gene Function -- Incomplete Dominance And Codominance -- Multiple Alleles -- Allelic Series -- Testing Gene Mutations For Allelism -- Solve It The Test For Allelism -- Variation Among The Effects Of Mutations -- Genes Function To Produce Polypeptides -- Focus On Genetic Symbols -- Why Are Some Mutations Dominant And Others Recessive? -- Gene Action: From Genotype To Phenotype -- Influence Of The Environment -- Environmental Effects On The Expression Of Human Genes -- Penetrance And Expressivity -- Gene Interactions -- Epistasis -- Pleiotropy -- Problem-Solving Skills Going From Pathways To Phenotypic Ratios -- Inbreeding: Another Look At Pedigrees -- The Effects Of Inbreeding -- Genetic Analysis Of Inbreeding"@en ;
   schema:description "Note continued: Concurrent Transcription, Translation, And Mrna Degradation -- Transcription And Rna Processing In Eukaryotes -- Five Rna Polymerases/Five Sets Of Genes -- On The Cutting Edge Chromatin Remodeling And Gene Expression -- Initiation Of Rna Chains -- Solve It Initiation Of Transcription By Rna Polymerase Ii In Eukaryotes -- Rna Chain Elongation And The Addition Of 5' Methyl Guanosine Caps -- Termination By Chain Cleavage And The Addition Of 3' Poly(A) Tails -- Solve It Formation Of The 3'-Terminus Of An Rna Polymerase Ii Transcript -- Rna Editing: Altering The Information Content Of Mrna Molecules -- Interrupted Genes In Eukaryotes: Exons And Introns -- Some Very Large Eukaryotic Genes -- Introns: Biological Significance? -- Removal Of Intron Sequences By Rna Splicing -- TRna Precursor Splicing: Unique Nuclease And Ligase Activities -- Autocatalytic Splicing -- Pre-Mrna Splicing: Snrnas, Snrnps, And The Spliceosome"@en ;
   schema:description "Note continued: Meiosis I -- Meiosis Ii And The Outcomes Of Meiosis -- Solve It How Many Chromosome Combinations In Sperm -- Life Cycles Of Some Model Genetic Organisms -- Saccharomyces Cerevisiae, Baker's Yeast -- Arabidopsis Thaliana, A Fast-Growing Plant -- Mus Musculus, The Mouse -- Problem-Solving Skills Counting Chromosomes And Chromatids -- ch. 3 Mendelism: The Basic Principles Of Inheritance -- The Birth Of Genetics: A Scientific Revolution -- Mendel's Study Of Heredity -- Mendel's Experimental Organism, The Garden Pea -- Monohybrid Crosses: The Principles Of Dominance And Segregation -- Dihybrid Crosses: The Principle Of Independent Assortment -- Applications Of Mendel's Principles -- The Punnett Square Method -- The Forked-Line Method -- The Probability Method -- Solve It Using Probabilities In A Genetic Problem -- Testing Genetic Hypotheses -- The Chi-Square Test -- Solve It Using The Chi-Square Test -- Mendelian Principles In Human Genetics -- Pedigrees"@en ;
   schema:description "Note continued: ch. 7 Linkage, Crossing Over, And Chromosome Mapping In Eukaryotes -- The World's First Chromosome Map -- Linkage, Recombination, And Crossing Over -- Early Evidence For Linkage And Recombination -- Crossing Over As The Physical Basis Of Recombination -- Evidence That Crossing Over Causes Recombination -- Chiasmata And The Time Of Crossing Over -- Chromosome Mapping -- Crossing Over As A Measure Of Genetic Distance -- Recombination Mapping With A Two-Point Testcross -- Recombination Mapping With A Three-Point Testcross -- Solve It Mapping Two Genes With Testcross Data -- Problem-Solving Skills Using A Genetic Map To Predict The Outcome Of A Cross -- Recombination Frequency And Genetic Map Distance -- Cytogenetic Mapping -- Localizing Genes Using Deletions And Duplications -- Genetic Distance And Physical Distance -- Solve It Cytological Mapping Of A Drosophila Gene -- Linkage Analysis In Humans -- Recombination And Evolution"@en ;
   schema:description "Note continued: Gene Expression And Chromatin Organization -- Solve It Using Rnai In Cell Research -- Euchromatin And Heterochromatin -- Molecular Organization Of Transcriptionally Active Dna -- Chromatin Remodeling -- Dna Methylation -- Imprinting -- On The Cutting Edge The Epigenetics Of Twins -- Activation And Inactivation Of Whole Chromosomes -- Inactivation Of X Chromosomes In Mammals -- Hyperactivation Of X Chromosomes In Drosophila -- Hypoactivation Of X Chromosomes In Caenorhabditis -- ch. 20 The Genetic Control Of Animal Development -- Stem-Cell Therapy -- A Genetic Perspective On Development -- Maternal Gene Activity In Development -- Maternal-Effect Genes -- Solve It A Maternal-Effect Mutation In The Cinnamon Gene -- Determination Of The Dorsal-Ventral And Anterior-Posterior Axes -- Zygotic Gene Activity In Development -- Body Segmentation -- Organ Formation -- Specification Of Cell Types -- Solve It Cave Blindness"@en ;
   schema:description "Note continued: Use Of Recombinant Dna Technology To Identify Human Genes And Diagnose Human Diseases -- Huntington's Disease -- Focus On Fragile X Syndrome And Expanded Trinucleotide Repeats -- Problem-Solving Skills Testing For Mutant Alleles That Cause Fragile X Mental Retardation -- Cystic Fibrosis -- Molecular Diagnosis Of Human Diseases -- Human Gene Therapy -- Dna Profiling -- Paternity Tests -- Solve It How Can Dna Profiles Be Used To Establish Identity? -- Forensic Applications -- Production Of Eukaryotic Proteins In Bacteria -- Human Growth Hormone -- Proteins With Industrial Applications -- Transgenic Plants And Animals -- Transgenic Animals: Microinjection Of Dna Into Fertilized Eggs And Transfection Of Embryonic Stem Cells -- Transgenic Plants: The T1 Plasmid Of Agrobacterium Tumefaciens -- Reverse Genetics: Dissecting Biological Processes By Inhibiting Gene Expression -- Knockout Mutations In The Mouse -- T-Dna And Transposon Insertions"@en ;
   schema:description "Note continued: Problem-Solving Skills Predicting Amino Acid Substitutions Induced By Mutagens -- A Nearly Universal Code -- Codon-Trna Interactions -- Recognition Of Codons By Trnas: The Wobble Hypothesis -- Suppressor Mutations That Produce Trnas With Altered Codon Recognition -- Solve It Effects Of Base-Pair Substitutions In The Coding Region Of The Hbb Gene -- On The Cutting Edge Selenocysteine, The 21St Amino Acid -- ch. 13 Mutation, Dna Repair, And Recombination -- Xeroderma Pigmentosum: Defective Repair Of Damaged Dna In Humans -- Mutation: Source Of The Genetic Variability Required For Evolution -- The Molecular Basis Of Mutation -- Solve It Nucleotide-Pair Substitutions In The Human Hbb Gene -- Induced Mutations -- Mutations Induced By Chemicals -- Mutations Induced By Radiation -- Problem-Solving Skills Predicting Amino Acid Changes Induced By Chemical Mutagens -- Mutations Induced By Transposable Genetic Elements"@en ;
   schema:description "Note continued: Evolutionary Significance Of Recombination -- Suppression Of Recombination By Inversions -- Genetic Control Of Recombination -- ch. 8 The Genetics Of Bacteria And Their Viruses -- Multi-Drug-Resistant Bacteria: A Ticking Timebomb? -- Viruses And Bacteria In Genetics -- The Genetics Of Viruses -- Bacteriophage T4 -- Bacteriophage Lambda -- The Genetics Of Bacteria -- Mutant Genes In Bacteria -- Unidirectional Gene Transfer In Bacteria -- Mechanisms Of Genetic Exchange In Bacteria -- Transformation -- Conjugation -- Plasmids And Episomes -- Problem-Solving Skills Mapping Genes Using Conjugation Data -- F'Factors And Sexduction -- Transduction -- Solve It How Can You Map Closely Linked Genes Using Partial Diploids -- The Evolutionary Significance Of Genetic Exchange In Bacteria -- Solve It How Do Bacterial Genomes Evolve? -- On The Cutting Edge Antibiotic-Resistant Bacteria -- ch. 9 Dna And The Molecular Structure Of Chromosomes -- Discovery Of Nuclein"@en ;
   schema:description "Note continued: Chromosome Walks And Jumps -- The Human Genome Project -- Mapping The Human Genome -- Sequencing The Human Genome -- The Human Hapmap Project -- Rna And Protein Assays Of Genome Function -- Expressed Sequences -- Microarrays And Gene Chips -- The Green Fluorescent Protein As A Reporter Of Protein Synthesis -- Comparative Genomics -- Bioinformatics -- Problem-Solving Skills Using Bioinformatics To Investigate Dna Sequences -- Prokaryotic Genomes -- A Living Bacterium With A Chemically Synthesized Genome -- The Genomes Of Chloroplasts And Mitochondria -- Solve It What Do We Know About The Mitochondrial Genome Of The Extinct Woolly Mammoth? -- Eukaryotic Genomes -- Solve It What Can You Learn About Dna Sequences Using Bioinformatics? -- Genome Evolution In The Cereal Grasses -- Genome Evolution In Mammals -- ch. 16 Applications Of Molecular Genetics -- Gene Therapy Improves Sight In Child With Congenital Blindness"@en ;
   schema:description "Machine generated contents note: ch. 1 The Science of Genetics -- The Personal Genome -- An Invitation -- Three Great Milestones in Genetics -- Mendel: Genes And The Rules Of Inheritance -- Watson And Crick: The Structure Of Dna -- The Human Genome Project: Sequencing Dna And Cataloguing Genes -- DNA as the Genetic Material -- Dna Replication: Propagating Genetic Information -- Gene Expression: Using Genetic Information -- Mutation: Changing Genetic Information -- Genetics and Evolution -- Levels of Genetic Analysis -- Classical Genetics -- Molecular Genetics -- Population Genetics -- Genetics in the World: Applications of Genetics to Human Endeavors -- Genetics In Agriculture -- Genetics In Medicine -- Genetics In Society -- ch. 2 Cellular Reproduction -- Dolly -- Cells and Chromosomes -- The Cellular Environment -- Prokaryotic And Eukaryotic Cells -- Chromosomes: Where Genes Are Located -- Cell Division -- Mitosis -- Meiosis -- Solve It How Much Dna In Human Meiotic Cells"@en ;
   schema:description "Note continued: Problem-Solving Skills The Effects Of Mutations During Eye Development -- Genetic Analysis Of Development In Vertebrates -- Vertebrate Homologues Of Invertebrate Genes -- The Mouse: Random Insertion Mutations And Gene-Specific Knockout Mutations -- Studies With Mammalian Stem Cells -- Reproductive Cloning -- Genetic Changes In The Differentiation Of Vertebrate Immune Cells -- ch. 21 The Genetic Basis Of Cancer -- A Molecular Family Connection -- Cancer: A Genetic Disease -- The Many Forms Of Cancer -- Cancer And The Cell Cycle -- Cancer And Programmed Cell Death -- A Genetic Basis For Cancer -- Oncogenes -- Tumor-Inducing Retroviruses And Viral Oncogenes -- Solve It The V-Erbb And V-Fms Viral Oncogenes -- Cellular Homologues Of Viral Oncogenes: The Proto-Oncogenes -- Mutant Cellular Oncogenes And Cancer -- Chromosome Rearrangements And Cancer -- Tumor Suppressor Genes -- Inherited Cancers And Knudson's Two-Hit Hypothesis"@en ;
   schema:description "Snustad's 6th edition of Principles of Genetics offers many new and advanced features including boxed sections with the latest advances in Genetics, a streamlined roster of topics, a more reader-friendly layout, and new problem-solving supplements."@en ;
   schema:description "Note continued: Unique Aspects Of Eukaryotic Chromosome Replication -- The Cell Cycle -- Multiple Replicons Per Chromosome -- Solve It Understanding Replication Of The Human X Chromosome -- Two Or More Dna Polymerases At A Single Replication Fork -- Duplication Of Nucleosomes At Replication Forks -- Telomerase: Replication Of Chromosome Termini -- Telomere Length And Aging In Humans -- ch. 11 Transcription And Rna Processing -- Storage And Transmission Of Information With Simple Codes -- Transfer Of Genetic Information: The Central Dogma -- Transcription And Translation -- Five Types Of Rna Molecules -- The Process Of Gene Expression -- An Mrna Intermediary -- General Features Of Rna Synthesis -- Problem-Solving Skills Distinguishing Rnas Transcribed From Viral And Host Dnas -- Transcription In Prokaryotes -- Rna Polymerases: Complex Enzymes -- Initiation Of Rna Chains -- Elongation Of Rna Chains -- Termination Of Rna Chains"@en ;
   schema:description "Note continued: Solve It Selection Against A Harmful Recessive Allele -- Random Genetic Drift -- Random Changes In Allele Frequencies -- The Effects Of Population Size -- Problem-Solving Skills Applying Genetic Drift To Pitcairn Island -- Populations In Genetic Equilibrium -- Balancing Selection -- Mutation-Selection Balance -- Mutation-Drift Balance -- ch. 24 Evolutionary Genetics -- D'Ou Venons Nous? Que Sommes Nous? Ou Allons Nous? -- The Emergence Of Evolutionary Theory -- Darwin's Theory Of Evolution -- Evolutionary Genetics -- Genetic Variation In Natural Populations -- Variation In Phenotypes -- Variation In Chromosome Structure -- Variation In Protein Structure -- Variation In Nucleotide Sequences -- Molecular Evolution -- Molecules As "Documents Of Evolutionary History" -- Molecular Phylogenies -- Rates Of Molecular Evolution -- Problem-Solving Skills Using Mitochondrial Dna To Establish A Phylogeny -- The Molecular Clock"@en ;
   schema:description "Note continued: Rna Interference -- Solve It How Might Rna Interference Be Used To Treat Burkitt's Lymphoma? -- ch. 17 Transposable Genetic Elements -- Maize: A Staple Crop With A Cultural Heritage -- Transposable Elements: An Overview -- Transposable Elements In Bacteria -- Is Elements -- Solve It Accumulating Drug-Resistance Genes -- Composite Transposons -- The Tn3 Element -- Cut-And-Paste Transposons In Eukaryotes -- Ac And Ds Elements In Maize -- P Elements And Hybrid Dysgenesis In Drosophila -- Problem-Solving Skills Analyzing Transposon Activity In Maize -- On The Cutting Edge Small Rnas Repress P Element Activity -- Retroviruses And Retrotransposons -- Retroviruses -- Retroviruslike Elements -- Retroposons -- Transposable Elements In Humans -- The Genetic And Evolutionary Significance Of Transposable Elements -- Transposons As Mutagens -- Genetic Transformation With Transposons -- Solve It Transposon-Mediated Chromosome Rearrangements"@en ;
   schema:description "Note continued: ch. 19 Regulation Of Gene Expression In Eukaryotes -- African Trypanosomes: A Wardrobe Of Molecular Disguises -- Ways Of Regulating Eukaryotic Gene Expression: An Overview -- Dimensions Of Eukaryotic Gene Regulation -- Controlled Transcription Of Dna -- Alternate Splicing Of Rna -- Solve It Counting Mrnas -- Cytoplasmic Control Of Messenger Rna Stability -- Induction Of Transcriptional Activity By Environmental And Biological Factors -- Temperature: The Heat-Shock Genes -- Signal Molecules: Genes That Respond To Hormones -- Molecular Control Of Transcription In Eukaryotes -- Dna Sequences Involved In The Control Of Transcription -- Proteins Involved In The Control Of Transcription: Transcription Factors -- Problem-Solving Skills Defining The Sequences Required For A Gene's Expression -- Posttranscriptional Regulation Of Gene Expression By Rna Interference -- Rnai Pathways -- Sources Of Short Interfering Rnas And Micrornas"@en ;
   schema:description "Note continued: Solve It Calculating Divergence Times -- Variation In The Evolution Of Protein Sequences -- Variation In The Evolution Of Dna Sequences -- The Neutral Theory Of Molecular Evolution -- Solve It Evolution By Mutation And Genetic Drift -- Molecular Evolution And Phenotypic Evolution -- Speciation -- What Is A Species? -- Modes Of Speciation -- Human Evolution -- Humans And The Great Apes -- Human Evolution In The Fossil Record -- Dna Sequence Variation And Human Origins -- Appendices -- Appendix A The Rules Of Probability -- Appendix B Binomial Probabilities -- Appendix C : In Situ Hybridization -- Appendix D Evidence For An Unstable Messenger Rna -- Appendix E Evolutionary Rates."@en ;
   schema:description "Note continued: Functions Of The Genetic Material -- Proof That Genetic Information Is Stored In Dna -- Proof That Dna Mediates Transformation -- Proof That Dna Carries The Genetic Information In Bacteriophage T2 -- Proof That Rna Stores The Genetic Information In Some Viruses -- The Structures Of Dna And Rna -- Nature Of The Chemical Subunits In Dna And Rna -- Dna Structure: The Double Helix -- Problem-Solving Skills Calculating Base Content In Dna -- Dna Structure: Alternate Forms Of The Double Helix -- Solve It What Are Some Important Features Of Double-Stranded Dna? -- Dna Structure: Negative Supercoils In Vivo -- Chromosome Structure In Prokaryotes And Viruses -- Chromosome Structure In Eukaryotes -- Chemical Composition Of Eukaryotic Chromosomes -- One Large Dna Molecule Per Chromosome -- Three Levels Of Dna Packaging In Eukaryotic Chromosomes -- Solve It How Many Nucleosomes In One Human X Chromosome -- Centromeres And Telomeres -- Repeated Dna Sequences"@en ;
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