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Prostate cancer

Author: Christopher J Sweeney
Publisher: Philadelphia : Elsevier, 2013.
Series: Clinics: Internal Medicine.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
This issue of Hematology/Oncology Clinics is focused on Prostate Cancer and highlights topics such as: Prevention, Early Detection, Biomarkers, Risk stratification, Imaging in Prostate Cancer, Adjuvant hormonal therapy, Management of patient with biochemical relapse, Management of patient with newly metastatic disease, and Bone Health Management.
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Prostate cancer
(OCoLC)868375994
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Christopher J Sweeney
ISBN: 9780323227230 0323227236 1336247118 9781336247116
OCLC Number: 910878944
Description: 1 online resource (xii, pages 1092-1295) : illustrations.
Contents: Front Cover; Prostate Cancer; Copyright; Contributors; Contents; Forthcoming Issues; Preface; Early Detection, PSA Screening, and Management of Overdiagnosis; Key points; Introduction; PSA screening; Randomized controlled trials of PSA screening; PSA screening modifications to improve detection; PSA refinements; PSA Velocity; Free PSA; Complexed PSA; PSA Density; Risk-based screening; Prediction tools; Novel screening tests; PCA3; Prostate Health Index; TMPRSS2:ERG Gene Fusion; Current screening guidelines; Overdiagnosis in prostate cancer; Impact of overdiagnosis. Watchful waiting and observationActive surveillance; Summary; References; Surgical Management of Prostate Cancer; Key points; Introduction; Patient selection; Surgical technique; Cavernosal nerve sparing; Pelvic lymph node dissection; Surgical margins; Low-risk prostate cancer; Definition of Low-Risk Prostate Cancer; Outcomes for Low-Risk Disease Following Radical Prostatectomy; High-risk prostate cancer; Definition of High-Risk Prostate Cancer; Outcomes for High-Risk Disease Following Radical Prostatectomy; Neoadjuvant therapy before radical prostatectomy. Is radical prostatectomy the preferred treatment for high-risk prostate cancer?Alternative Surgical Therapies; Summary; References; Contemporary Issues in Radiotherapy for Clinically Localized Prostate Cancer; Key points; Introduction; Principles of radiation therapy; Patient selection for radiation therapy with curative intent; Risk Stratification; Assessment, Comorbidities, and Contraindications; Defining the radiation target; Prostate and Seminal Vesicles; Whole Pelvic Irradiation; External Beam Radiotherapy; IMRT; Image-Guided Radiation Therapy; Dose-Escalated Radiotherapy; Toxicity. Role of Androgen Deprivation TherapyBrachytherapy; LDR Brachytherapy; Patient selection for brachytherapy; Outcomes; Toxicity; HDR Brachytherapy; Toxicity; Postprostatectomy radiotherapy; PPRT Volume Delineation; Adjuvant Therapy; Salvage Therapy; PPRT Toxicity (Adjuvant and Salvage); Ongoing Trials; Second malignancy risks from radiotherapy; Future directions in prostate radiotherapy; Anatomic and Molecular Imaging; Hypofractionation; Stereotactic Body Radiotherapy; New Endocrine Therapies; Summary; References; Imaging in Prostate Carcinoma; Key points; Introduction. Imaging modalities commonly used to evaluate prostate cancerTRUS; MRI; CT; Skeletal Scintigraphy (99mTc-MDP Bone Scan); PET; Imaging in staging and management of prostate cancer: localized and metastatic disease; Future directions; DCE-MRI; MRSI; DWI; mpMRI; PET; Summary; References; Neoadjuvant and Adjuvant Hormonal and Chemotherapy for Prostate Cancer; Key points; Introduction; Adjuvant hormone therapy following prostatectomy; Adjuvant RT following prostatectomy; Adjuvant androgen deprivation therapy in combination with RT; Adjuvant chemotherapy.
Series Title: Clinics: Internal Medicine.
Responsibility: editor, Christopher J. Sweeney ; consulting editors, George P. Canellos, H. Franklin Bunn.

Abstract:

Focuses on Prostate Cancer and highlights topics such as: Prevention, Early Detection, Biomarkers, Risk stratification, Imaging in Prostate Cancer, Adjuvant hormonal therapy, Management of patient  Read more...

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