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Proteogenomics

Author: Mohamed A Selmy
Publisher: Ashland : Delve Publishing, 2019.
Edition/Format:   eBook : Document : English
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Selmy, Mohamed A.
Proteogenomics.
Ashland : Delve Publishing, ©2019
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Mohamed A Selmy
ISBN: 9781773618012 1773618016
OCLC Number: 1085235556
Description: 1 online resource (250 pages)
Contents: Cover; Half Title Page; Title Page; Copyright Page; About The Author; Table of Contents; List of Figures; List of Tables; List of Abbreviations; Preface; Chapter 1 Introduction to Proteogenomics; References; Chapter 2 Modern Omic Technologies; 2.1. Genomic Technologies; 2.2. Transcriptome Analysis; 2.3. Proteomic Analysis; References; Chapter 3 Proteomics Bioinformatics Tools in Proteogenomics Studies; 3.1. Introduction; 3.2. Database Search Engines; 3.3. Results Integration; 3.4. Limitations In Database Searching; 3.5. Application To Proteogenomics; 3.6. Conclusion; References Chapter 4 Proteogenomics Softwares4.1. Proteogenomics Software; References; Chapter 5 Mutant Proteogenomics; 5.1. Introduction; 5.2. Theoretical Considerations; 5.3. Methodologies For Detection Of Mutant Proteins; 5.4. Biological Findings; References; Chapter 6 Proteogenomics Analysis In Cancer Research; 6.1. Introduction; 6.2. Bioinformatics Tools For SAP In Cancer Detection; 6.3. Proteogenomics Methods For The Identification of SAPs Using Shotgun Experiments; 6.4. Summary; References; Chapter 7 Proteogenomics Analysis Of Oncogenic Mutations; 7.1. Introduction 7.2. Lung Cancer Subtypes And Mutations7.3. Clinical Proteogenomics; 7.4. Development Of Proteogenomics Technologies To Identify/Quantify Mutated Proteins; 7.5. Cellular Pathways Affected By Somatic Mutations; 7.6. Drug Resistance And Gatekeeper Mutations; 7.7. Perspective; References; Chapter 8 Proteogenomics For Environmental Microbiology; 8.1. Introduction; 8.2 An Evaluation Of Errors Occurring During Genome Sequencing and Annotation; 8.3. Proteogenomics Is Targeting At Better Annotation of Gene Structures; 8.4. N-Terminomics Is The Tool To Success 8.5. Should We Trust In Proteogenomics Results?8.6. Extending The Notions of Proteogenomics; 8.7. Potentials In Environmental Microbiology; References; Chapter 9 Proteogenomics For The Analysis Of Human Antibody Repertoires; 9.1. Introduction; 9.2. Proteogenomics; 9.3. Analysis Methods For Sequencing Immunoglobulin Genes; 9.4. De Novo Protein Sequencing of Monoclonal Antibodies; 9.5. Native Mass Spectrometry; 9.6. Clinical Potentials of Proteogenomics Approaches; 9.7. Conclusions; References; Chapter 10 Concluding Marks; Index

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