Re-examining subfamily classifications for the Alu family of repeated DNA sequences (Book, 1994) [WorldCat.org]
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Re-examining subfamily classifications for the Alu family of repeated DNA sequences

Author: William A York; Haven C Sweet; University of Central Florida. College of Arts and Sciences. Biology.
Publisher: Orlando, Florida : University of Central Florida, 1994.
Dissertation: M.S. University of Central Florida 1994.
Series: Retrospective Theses and Dissertations (University of Central Florida)
Edition/Format:   Thesis/dissertation : Document : Thesis/dissertation : State or province government publication : eBook   Computer File : English
Summary:
The primate Alu family of repetitive elements has been widely characterized. This ubiquitous class of retroposons has been found to occupy some 5% of the human genome. This heterogenous group of Short Interspersed Nucleic acid Elements (SINEs) has been theorized to possess an identifiable subfamily structure between and within various taxonomic levels in primates. It has been postulated that humans possess up to 6  Read more...
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Details

Material Type: Document, Thesis/dissertation, Government publication, State or province government publication, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: William A York; Haven C Sweet; University of Central Florida. College of Arts and Sciences. Biology.
OCLC Number: 1122933424
Reproduction Notes: Electronic reproduction. [Florida] : University of Central Florida, 2011 Mode of access: World Wide Web. System requirements: Internet connectivity; Web browser software; Adobe Acrobat Reader to view and print PDF files. Electronically reproduced by the University of Central Florida from a book held in the Main Library at the University of Central Florida, Orlando.
Description: 1 online resource (viii, 65 leaves).
Series Title: Retrospective Theses and Dissertations (University of Central Florida)
Responsibility: by William A. York.

Abstract:

The primate Alu family of repetitive elements has been widely characterized. This ubiquitous class of retroposons has been found to occupy some 5% of the human genome. This heterogenous group of Short Interspersed Nucleic acid Elements (SINEs) has been theorized to possess an identifiable subfamily structure between and within various taxonomic levels in primates. It has been postulated that humans possess up to 6 Alu subfamilies in their genome; this number, however, has varied according to the method of analysis performed on the data. Quentin (1988) analyzed 127 aligned Alu sequences and found evidence supporting the amplification/ fixation theory in 5 subfamilies. The research presented in this thesis posits that Quentin's method of alignment used in the correspondence analysis is questionable. A re-examination using an alternative, perhaps more tenable, alignment of the Alu sequences may allow for a more lucid and accurate identification of Alu subfamily structure in the human genome.

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