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Recent trends in cancer biology : spotlight on signaling cascades and microRNAs : cell signaling pathways and microRNAs in cancer biology

Author: Sundas Fayyaz; Ammad Ahmad Farooqi
Publisher: Cham, Switzerland : Springer, 2018.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Cancer is a multifaceted disease and overwhelmingly increasing experimental evidence has helped us to develop a deeper understanding of the role of signal transduction cascades in cancer development and progression. Tissue microarrays and next generation sequencing technologies have assisted us to gather missing pieces of jigsaw puzzle and we now know that deregulation of spatio-temporally controlled signaling  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Printed edition:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Sundas Fayyaz; Ammad Ahmad Farooqi
ISBN: 9783319715537 3319715534
OCLC Number: 1028552943
Notes: Includes index.
Description: 1 online resource
Contents: 1. From Endometriosis to Cancer: Spotlight on Intracellular Signaling Cascades and MicroRNAs2. Tyrosine kinases, microRNAs, epigenetics: new insights in the mechanisms of leukemogenesis3. The emerging role of exosomes in cancer progression and their potential as therapy targets4. Tranquilizing and Awakening ATM to Promote Killing of Cancer Cells5. The Role of GPER Signaling in Carcinogenesis: a Focus on Prostate Cancer6. Bone Cancer: Dysregulation of Signaling Cascades by microRNAs7. The roles of miR-25 and its targeted genes in human cancer8. Notch Signaling in Lung Cancer Initiation and Development9. TGF-ss/Smad signalling pathway in cancer10. Natural Agents Mediated Regulation of microRNAs: Do We Need Skilled Archers to Hit the Bullseye11. Sebaceous Carcinoma of the Eyelid12. Current knowledge of miRNAs as biomarkers in Breast Cancer13. Signaling Landscape of AML: The Story So Far14. When the molecules start playing chess, or how microRNAs acquire dualistic activity during cancer progression15. The Crosstalk Between miRNAs and Autophagy in Cancer Progression16. Role of CEACAM in Different CancersIndex
Responsibility: Sundas Fayyaz, Ammad Ahmad Farooqi, editors.

Abstract:

Cancer is a multifaceted disease and overwhelmingly increasing experimental evidence has helped us to develop a deeper understanding of the role of signal transduction cascades in cancer development  Read more...

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