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Robust networks : from graphs to systems biology

Author: Animesh Ray; Alpan Raval
Publisher: Boca Raton, Fla. ; London : Chapman & Hall/CRC, 2007.
Series: Wiley series in mathematical and computational biology.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:

Discusses general principles behind network models and the essential concepts in mathematical modeling of molecular regulatory networks in biology. This book relates abstract concepts in  Read more...

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Document Type: Book
All Authors / Contributors: Animesh Ray; Alpan Raval
ISBN: 9781584884637 1584884630
OCLC Number: 85829962
Description: pages cm.
Contents: The Living Interactome Biological Function Depends on Context The Nature of Interactions Network as a Metaphor in Biology Metabolic Networks Robustness at the Network Level Experimental Inference of Interactions Direct versus Indirect Inference of Interactions Physical versus Genetic Interactions The Two-Hybrid Interaction Affinity Co-Purification DNA-Protein Interactions Classification and Interpretation of Genetic Interactions Inference of Genetic Interactions Prediction of Physical Interactions Entropy and Information Boolean Networks REVEAL Regulatory Interactions Variants of the REVEAL Method Dynamic Bayesian Networks Predicting Protein-Protein InteractionsData Integration to Improve Prediction PerformanceMetabolic Networks and Genetic Interactions Optimal Metabolic States and Flux Balance Analysis Minimization of Metabolic Adjustment and Gene DeletionsPredicting Genetic Interactions among Metabolic Genes General Methods for Predicting Genetic InteractionsApproaches for Integrated Prediction of NetworksTesting Inferred Networks Co-Expression as a Test of Physical Interaction An Experimental Test of Predicted Protein-Protein InteractionsCombining Protein Interactions Discovered by High-Throughput ExperimentsFrom Curated Protein-Protein Interactions to Protein ComplexesTesting DNA-Protein InteractionsCongruence of Biological Function among Interacting PartnersTesting Genetic InteractionsStructure-Based Tests of InteractionSmall Model Networks Life Cycle of the Lambda PhageInteraction Network in the Lysis-Lysogeny DecisionRecruitment of Proteins as a Theme in Regulatory NetworksThe Network of Cell Cycle RegulationTractable Models of Large NetworksModels of Regular NetworksRandom Network ModelsEvolving Networks by Preferential AttachmentEvolving Networks Based on Gene DuplicationReconstruction of Ancient Networks from Modern Ones Large-Scale Biophysics-Inspired Models for Protein Interaction NetworksNetwork Modularity and Robustness Modularity Implies Robustness in the Drosophila Segment Polarity NetworkTopological and Functional Aspects of Network ModularityRobustness Implications of Topology of Biological NetworksRobustness and Network Dynamics Network Robustness by Rewiring Networks and Disease Disease Loci Identification and Mapping Network as a Paradigm for Linking Diseases and Disease Genes Network-Based Prediction of Disease Genes Network Analysis of Disease Mechanisms and Disease Response Network-Based Prediction of Disease Comorbidity Cancer and Synthetic Lethality
Series Title: Wiley series in mathematical and computational biology.
Responsibility: Animesh Ray and Alpan Raval.

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"Raval and Ray provide a comprehensive and modern exposition of a rapidly evolving field: network biology. This text will help biology, mathematics, and computer science students alike to become Read more...

 
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