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Sequence - evolution - function : computational approaches in comparative genomics Náhled dokumentu
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Sequence - evolution - function : computational approaches in comparative genomics

Autor Eugene V Koonin; Michael Y Galperin; National Center for Biotechnology Information (U.S.)
Vydavatel: Boston, Mass. : Kluwer, ©2003.
Vydání/formát:   e-kniha : Document : EnglishZobrazit všechny vydání a formáty
Shrnutí:
Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function  Přečíst více...
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Žánr/forma: Electronic books
Doplňující formát: Print version:
Koonin, Eugene V.
Sequence - evolution - function.
Boston : Kluwer Academic, ©2003
(DLC) 2002034045
(OCoLC)50561948
Typ materiálu: Document, Internetový zdroj
Typ dokumentu Internetový zdroj, Počítačový soubor
Všichni autoři/tvůrci: Eugene V Koonin; Michael Y Galperin; National Center for Biotechnology Information (U.S.)
ISBN: 9781475737837 1475737831
OCLC číslo: 55642057
Poznámka o jazyku: English.
Popis: 1 online resource (xiii, 461 pages, 11 unnumbered pages of plates) : illustrations (some color)
Obsahy: Genomics: From Phage to Human --
Evolutionary Concept in Genetics and Genomics --
Information Sources for Genomics --
Principles and Methods of Sequence Analysis --
Genome Annotation and Analysis --
Comparative Genomics and New Evolutionary Biology --
Evolution of Central Metabolic Pathways: The Playground of Non-Orthologous Gene Displacement --
Genomes and the Protein Universe --
Epilogue: Peering through the Crystal Ball.
Jiné tituly: Computational approaches in comparative genomics
Odpovědnost: by Eugene V. Koonin and Michael Y. Galperin.

Anotace:

Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics.  Přečíst více...

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Primary Entity<\/h3>\n
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# Evolutionary genetics<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/genome<\/a>> ; # Genome<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/genetics<\/a>> ; # Genetics<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/computational_biology_methods<\/a>> ; # Computational Biology--methods<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/biological_phenomena<\/a>> ; # Biological Phenomena<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/disciplines_and_occupations<\/a>> ; # Disciplines and Occupations<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/genomics<\/a>> ; # Genomics<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/genomes<\/a>> ; # Genomes<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/genetic_techniques<\/a>> ; # Genetic Techniques<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/biology<\/a>> ; # Biology<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/investigative_techniques<\/a>> ; # Investigative Techniques<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/genome_mesh<\/a>> ; # Genome [MESH]<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/sequence_analysis_mesh<\/a>> ; # Sequence Analysis [MESH]<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/health_&_biological_sciences<\/a>> ; # Health & Biological Sciences<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/genetic_phenomena<\/a>> ; # Genetic Phenomena<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/sequence_analysis<\/a>> ; # Sequence Analysis<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/nucleotide_sequence<\/a>> ; # Nucleotide sequence<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/dewey.info\/class\/572.86\/e21\/<\/a>> ;\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/analytical_diagnostic_and_therapeutic_techniques_and_equipment<\/a>> ; # Analytical, Diagnostic and Therapeutic Techniques and Equipment<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/genomics_mesh<\/a>> ; # Genomics [MESH]<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/biological_evolution_mesh<\/a>> ; # Biological Evolution [MESH]<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/evolution<\/a>> ; # Evolution<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/computational_biology_methods_mesh<\/a>> ; # Computational Biology--methods [mesh]<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/genetic_structures<\/a>> ; # Genetic Structures<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/biological_science_disciplines<\/a>> ; # Biological Science Disciplines<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/natural_science_disciplines<\/a>> ; # Natural Science Disciplines<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/phenomena_and_processes<\/a>> ; 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Galperin<\/span>\n\u00A0\u00A0\u00A0\nschema:copyrightYear<\/a> \"2003<\/span>\" ;\u00A0\u00A0\u00A0\nschema:creator<\/a> <http:\/\/viaf.org\/viaf\/12560215<\/a>> ; # Eugene V. Koonin<\/span>\n\u00A0\u00A0\u00A0\nschema:datePublished<\/a> \"2003<\/span>\" ;\u00A0\u00A0\u00A0\nschema:description<\/a> \"Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the \"digital divide\" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user\'s viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. 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Related Entities<\/h3>\n
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<http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/biological_phenomena<\/a>> # Biological Phenomena<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Biological Phenomena<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
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<http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/computational_biology_methods<\/a>> # Computational Biology--methods<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Computational Biology--methods<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
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<http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/disciplines_and_occupations<\/a>> # Disciplines and Occupations<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Disciplines and Occupations<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/evolution<\/a>> # Evolution<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Evolution<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/evolutionary_genetics<\/a>> # Evolutionary genetics<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Evolutionary genetics<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/genetic_phenomena<\/a>> # Genetic Phenomena<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Genetic Phenomena<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/genetic_structures<\/a>> # Genetic Structures<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Genetic Structures<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/genetic_techniques<\/a>> # Genetic Techniques<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Genetic Techniques<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/genetics<\/a>> # Genetics<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Genetics<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/genome<\/a>> # Genome<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Genome<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/genome_mesh<\/a>> # Genome [MESH]<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Genome [MESH]<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/genomes<\/a>> # Genomes<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Genomes<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/genomics<\/a>> # Genomics<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Genomics<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/genomics_mesh<\/a>> # Genomics [MESH]<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Genomics [MESH]<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/health_&_biological_sciences<\/a>> # Health & Biological Sciences<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Health & Biological Sciences<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/investigative_techniques<\/a>> # Investigative Techniques<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Investigative Techniques<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/natural_science_disciplines<\/a>> # Natural Science Disciplines<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Natural Science Disciplines<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/nucleotide_sequence<\/a>> # Nucleotide sequence<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Nucleotide sequence<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/phenomena_and_processes<\/a>> # Phenomena and Processes<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Phenomena and Processes<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/sequence_analysis<\/a>> # Sequence Analysis<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Sequence Analysis<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/792431813#Topic\/sequence_analysis_mesh<\/a>> # Sequence Analysis [MESH]<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Sequence Analysis [MESH]<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/id.loc.gov\/vocabulary\/countries\/mau<\/a>>\u00A0\u00A0\u00A0\u00A0a \nschema:Place<\/a> ;\u00A0\u00A0\u00A0\ndcterms:identifier<\/a> \"mau<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/viaf.org\/viaf\/12560215<\/a>> # Eugene V. Koonin<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Person<\/a> ;\u00A0\u00A0\u00A0\nschema:familyName<\/a> \"Koonin<\/span>\" ;\u00A0\u00A0\u00A0\nschema:givenName<\/a> \"Eugene V.<\/span>\" ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Eugene V. Koonin<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/viaf.org\/viaf\/149881801<\/a>> # National Center for Biotechnology Information (U.S.)<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Organization<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"National Center for Biotechnology Information (U.S.)<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/viaf.org\/viaf\/24855711<\/a>> # Michael Y. Galperin<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Person<\/a> ;\u00A0\u00A0\u00A0\nschema:familyName<\/a> \"Galperin<\/span>\" ;\u00A0\u00A0\u00A0\nschema:givenName<\/a> \"Michael Y.<\/span>\" ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Michael Y. Galperin<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/worldcat.org\/isbn\/9781475737837<\/a>>\u00A0\u00A0\u00A0\u00A0a \nschema:ProductModel<\/a> ;\u00A0\u00A0\u00A0\nschema:isbn<\/a> \"1475737831<\/span>\" ;\u00A0\u00A0\u00A0\nschema:isbn<\/a> \"9781475737837<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/www.worldcat.org\/oclc\/50561948<\/a>>\u00A0\u00A0\u00A0\u00A0a \nschema:CreativeWork<\/a> ;\u00A0\u00A0\u00A0\nrdfs:label<\/a> \"Sequence - evolution - function.<\/span>\" ;\u00A0\u00A0\u00A0\nschema:description<\/a> \"Print version:<\/span>\" ;\u00A0\u00A0\u00A0\nschema:isSimilarTo<\/a> <http:\/\/www.worldcat.org\/oclc\/55642057<\/a>> ; # Sequence - evolution - function : computational approaches in comparative genomics<\/span>\n\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/www.worldcat.org\/title\/-\/oclc\/55642057<\/a>>\u00A0\u00A0\u00A0\u00A0a \ngenont:InformationResource<\/a>, genont:ContentTypeGenericResource<\/a> ;\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/www.worldcat.org\/oclc\/55642057<\/a>> ; # Sequence - evolution - function : computational approaches in comparative genomics<\/span>\n\u00A0\u00A0\u00A0\nschema:dateModified<\/a> \"2019-12-15<\/span>\" ;\u00A0\u00A0\u00A0\nvoid:inDataset<\/a> <http:\/\/purl.oclc.org\/dataset\/WorldCat<\/a>> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n