skip to content
Sex and the developing brain Preview this item
ClosePreview this item
Checking...

Sex and the developing brain

Author: Margaret M McCarthy
Publisher: [San Rafael, Calif.] : Morgan & Claypool Life Sciences, ©2017 [2017]
Series: Colloquium series on the developing brain, bk. #14.
Edition/Format:   Print book : English : Second editionView all editions and formats
Summary:
The brains of males and females, men and women, are different, that is a fact. What is debated is how different and how important are those differences. Sex differences in the brain are determined by genetics, hormones, and experience, which in humans includes culture, society, and parental and peer expectations. The importance of nonbiological variables to sex differences in humans is paramount, making it difficult  Read more...
Rating:

(not yet rated) 0 with reviews - Be the first.

Subjects
More like this

Find a copy in the library

&AllPage.SpinnerRetrieving; Finding libraries that hold this item...

Details

Document Type: Book
All Authors / Contributors: Margaret M McCarthy
ISBN: 9781615047284 161504728X
OCLC Number: 1005934431
Description: xi, 139 pages : color illustrations ; 24 cm.
Contents: Introduction --
Sex differences in brain and behavior in context --
Sex determination versus sex differentiation --
Masculinization, feminization, and defeminization --
Steroid hormones are potent modulators of brain development --
Sex differences in the brain are established during a developmental sensitive window --
Sex differences in reproductive physiology and behavior are coordinated --
Steroid influence multiple endpoints via multiple mechanism to organize the brain --
Cellular mechanisms of steroid-mediated organization of the brain --
Ultrasonic vocalization differ in neonatal males and females because of a gene called FoxP2 --
Overcoming the hegemony of hormones : genes matter too --
Winged messengers : lesson from birds and files --
Sexual differentiation of the primate brain --
Sexual differentiation of the human brain --
Imaging studies give insight into brain sex differences --
Steroids and human brain development --
The value of understanding the effect of sex on the developing brain.
Series Title: Colloquium series on the developing brain, bk. #14.
Responsibility: Margaret M. McCarthy.

Abstract:

Sex differences in the brain are determined by genetics, hormones, and experience, which in humans includes culture, society, and parental and peer expectations. The importance of nonbiological  Read more...

Reviews

User-contributed reviews
Retrieving GoodReads reviews...
Retrieving DOGObooks reviews...

Tags

Be the first.
Confirm this request

You may have already requested this item. Please select Ok if you would like to proceed with this request anyway.

Linked Data


Primary Entity

<http://www.worldcat.org/oclc/1005934431> # Sex and the developing brain
    a schema:CreativeWork, schema:Book ;
    library:oclcnum "1005934431" ;
    library:placeOfPublication <http://id.loc.gov/vocabulary/countries/cau> ;
    schema:about <http://experiment.worldcat.org/entity/work/data/773906386#Topic/brain_growth> ; # Brain--Growth
    schema:about <http://experiment.worldcat.org/entity/work/data/773906386#Topic/steroids> ; # Steroids
    schema:about <http://experiment.worldcat.org/entity/work/data/773906386#Topic/brain_sex_differences> ; # Brain--Sex differences
    schema:about <http://experiment.worldcat.org/entity/work/data/773906386#Topic/brain_physiology> ; # Brain--physiology
    schema:about <http://experiment.worldcat.org/entity/work/data/773906386#Topic/sex_differentiation> ; # Sex Differentiation
    schema:about <http://experiment.worldcat.org/entity/work/data/773906386#Topic/developmental_neurobiology> ; # Developmental neurobiology
    schema:author <http://experiment.worldcat.org/entity/work/data/773906386#Person/mccarthy_margaret_m_1958> ; # Margaret M. McCarthy
    schema:bookEdition "Second edition." ;
    schema:bookFormat bgn:PrintBook ;
    schema:copyrightYear "2017" ;
    schema:datePublished "2017" ;
    schema:description "The brains of males and females, men and women, are different, that is a fact. What is debated is how different and how important are those differences. Sex differences in the brain are determined by genetics, hormones, and experience, which in humans includes culture, society, and parental and peer expectations. The importance of nonbiological variables to sex differences in humans is paramount, making it difficult if not impossible to parse out those contributions that are truly biological. The study of animals provides us the opportunity to understand the magnitude and scope of biologically based sex differences in the brain, and understanding the cellular mechanisms provides us insight into novel sources of brain plasticity. Many sex differences are established during a developmental sensitive window by differences in the hormonal milieu of males versus females. The neonatal testis produces large amounts of testosterone which gains access to the brain and is further metabolized into active androgens and estrogens which modify brain development. Major parameters that are influenced by hormones include neurogenesis, cell death, neurochemical phenotype, axonal and dendritic growth, and synaptogenesis. Variance in these parameters results in sex differences in the size of particular brain regions, the projections between brain regions, and the number and type of synapses within particular brain regions. The cellular mechanisms are both region and endpoint specific and invoke many surprising systems such as prostaglandins, endocannabinoids, and cell death proteins. Epigenetic modifications to the genome both establish and maintain sex differences in the brain and behavior. By understanding when, why, and how sex differences in the brain are established, we may also learn the source of strong gender biases in the relative risk and severity of numerous neurological diseases and disorders of mental health. Boys are much more likely to be diagnosed with autism spectrum or attention and hyperactivity disorders, as well as speech and language deficits, compared to girls. By contrast, women are more likely to suffer from affective disorders, such as depression, anxiety, compulsion, and eating disorders and more likely to experience autoimmune and neurodegenerative disorders. Schizophrenia with an early onset is more common in males but a late-onset version is markedly more frequent in females. Male biased disorders have origins in development while female biased disorders are almost exclusively post-puberty. This remarkable shift in disease risk demands our attention. Novel insights into the biological origins of disease are also gained by comparing and contrasting the same processes in different sexes."@en ;
    schema:description "Introduction -- Sex differences in brain and behavior in context -- Sex determination versus sex differentiation -- Masculinization, feminization, and defeminization -- Steroid hormones are potent modulators of brain development -- Sex differences in the brain are established during a developmental sensitive window -- Sex differences in reproductive physiology and behavior are coordinated -- Steroid influence multiple endpoints via multiple mechanism to organize the brain -- Cellular mechanisms of steroid-mediated organization of the brain -- Ultrasonic vocalization differ in neonatal males and females because of a gene called FoxP2 -- Overcoming the hegemony of hormones : genes matter too -- Winged messengers : lesson from birds and files -- Sexual differentiation of the primate brain -- Sexual differentiation of the human brain -- Imaging studies give insight into brain sex differences -- Steroids and human brain development -- The value of understanding the effect of sex on the developing brain."@en ;
    schema:exampleOfWork <http://worldcat.org/entity/work/id/773906386> ;
    schema:inLanguage "en" ;
    schema:isPartOf <http://experiment.worldcat.org/entity/work/data/773906386#Series/colloquium_digital_library_of_life_sciences_colloquium_series_on_the_developing_brain> ; # Colloquium digital library of life sciences. Colloquium series on the developing brain ;
    schema:isPartOf <http://experiment.worldcat.org/entity/work/data/773906386#Series/colloquium_series_on_the_developing_brain> ; # Colloquium series on the developing brain ;
    schema:name "Sex and the developing brain"@en ;
    schema:productID "1005934431" ;
    schema:workExample <http://worldcat.org/isbn/9781615047284> ;
    wdrs:describedby <http://www.worldcat.org/title/-/oclc/1005934431> ;
    .


Related Entities

<http://experiment.worldcat.org/entity/work/data/773906386#Person/mccarthy_margaret_m_1958> # Margaret M. McCarthy
    a schema:Person ;
    schema:birthDate "1958" ;
    schema:familyName "McCarthy" ;
    schema:givenName "Margaret M." ;
    schema:name "Margaret M. McCarthy" ;
    .

<http://experiment.worldcat.org/entity/work/data/773906386#Series/colloquium_digital_library_of_life_sciences_colloquium_series_on_the_developing_brain> # Colloquium digital library of life sciences. Colloquium series on the developing brain ;
    a bgn:PublicationSeries ;
    schema:hasPart <http://www.worldcat.org/oclc/1005934431> ; # Sex and the developing brain
    schema:name "Colloquium digital library of life sciences. Colloquium series on the developing brain ;" ;
    .

<http://experiment.worldcat.org/entity/work/data/773906386#Series/colloquium_series_on_the_developing_brain> # Colloquium series on the developing brain ;
    a bgn:PublicationSeries ;
    schema:hasPart <http://www.worldcat.org/oclc/1005934431> ; # Sex and the developing brain
    schema:name "Colloquium series on the developing brain ;" ;
    .

<http://experiment.worldcat.org/entity/work/data/773906386#Topic/brain_physiology> # Brain--physiology
    a schema:Intangible ;
    schema:name "Brain--physiology"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/773906386#Topic/brain_sex_differences> # Brain--Sex differences
    a schema:Intangible ;
    schema:name "Brain--Sex differences"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/773906386#Topic/developmental_neurobiology> # Developmental neurobiology
    a schema:Intangible ;
    schema:name "Developmental neurobiology"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/773906386#Topic/sex_differentiation> # Sex Differentiation
    a schema:Intangible ;
    schema:name "Sex Differentiation"@en ;
    .

<http://worldcat.org/isbn/9781615047284>
    a schema:ProductModel ;
    schema:isbn "161504728X" ;
    schema:isbn "9781615047284" ;
    .


Content-negotiable representations

Close Window

Please sign in to WorldCat 

Don't have an account? You can easily create a free account.