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Site-directed insertion of transgenes แสดงตัวอย่างรายการนี้
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Site-directed insertion of transgenes

ผู้แต่ง: Sylvaine Renault; Philippe Duchateau
สำนักพิมพ์: Dordrecht ; New York : Springer, ©2013.
ชุด: Topics in current genetics, 23.
ครั้งที่พิมพ์/รูปแบบ:   หนังสืออีเล็กทรอนิกส์ : เอกสาร : ภาษาอังกฤษดูครั้งที่พิมพ์และรูปแบบ
ฐานข้อมูล:WorldCat
สรุป:
The post-genomic era has brought new challenges and opportunities in all fields of the biology. In this context, several genome engineering technologies have emerged that will help deciphering genes function by as well as improve gene therapy strategies. Genomic modifications such as knock-in, knock-out, knock-down, sequence replacement or modification can today be routinely performed. However, in front of this  อ่านมากขึ้น…
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ประเภท/แบบฟอร์ม Electronic books
ขนิดวัสดุ: เอกสาร, ทรัพยากรอินแทอร์เน็ต
ประเภทของเอกสาร: แหล่งข้อมูลอินเทอร์เน็ต, ไฟล์คอมพิวเตอร์
ผู้แต่งทั้งหมด : ผู้แต่งร่วม Sylvaine Renault; Philippe Duchateau
ISBN: 9789400745315 9400745311 9400745303 9789400745308
OCLC Number: 806230393
คำอธิบาย: 1 online resource.
สารบัญ: Transgene Site-Specific Integration: Problems and Solutions / Solenne Bire and Florence Rouleux-Bonnin --
Designing Non-viral Targeted Integrating Vectors for Genome Engineering in Vertebrates / Ludivine Sinzelle and Nicolas Pollet --
Gene Targeting and Homologous Recombination in Saccharomyces cerevisiae / Judith Miné-Hattab and Rodney Rothstein --
Homologous Recombination in Mammals / Aurélia Barascu, Anastazja Grabarz and Bernard S. Lopez --
Engineered Zinc Finger Nucleases for Targeted Genome Editing / Cherie L. Ramirez and J. Keith Joung --
Engineered Meganucleases for Genome Engineering Purposes / Jean Charles Epinat, George H. Silva, Frédéric Pâques, Julianne Smith and Philippe Duchateau --
Cre/loxP, Flp/FRT Systems and Pluripotent Stem Cell Lines / Candice G.T. Tahimic, Kenji Sakurai, Kazuhiro Aiba and Norio Nakatsuji --
Site-Specific Recombination Using PhiC31 Integrase / Jonathan M. Geisinger and Michele P. Calos --
Modified Transposases for Site-Directed Insertion of Transgenes / Sean Colloms and Sylvaine Renault --
Targeted Plasmid Integration into the Human Genome by Engineered Recombinases / Charles A. Gersbach and Carlos F. Barbas III --
Gene Site-Specific Insertion in Plants / Olivier Da Ines and Charles I. White --
Site-Directed Insertion of Transgenes in Drosophila / Dana Carroll --
Nuclease Mediated Targeted Genome Modification in Mammalian Cells / Jenny C. Barker, Richard A. Voit and Matthew H. Porteus --
Bio-applications Derived from Site-Directed Genome Modification Technologies / Christophe Delenda, Sébastien Paris, Sylvain Arnould, Edward Balbirnie and Jean-Pierre Cabaniols.
ชื่อชุด: Topics in current genetics, 23.
ความรับผิดชอบ: Sylvaine Renault, Philippe Duchateau [editors].
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บทคัดย่อ:

This book surveys the field from mechanisms of site-directed modifications to application in organisms such as bacteria, yeast, plants, insects and mammals. Covers technologies based on Zinc Finger  อ่านมากขึ้น…

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