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Small molecules in hematology

Author: Uwe M Martens
Publisher: Cham, Switzerland : Springer, 2018.
Series: Recent results in cancer research, v. 212.
Edition/Format:   eBook : Document : English : Third editionView all editions and formats
Summary:
This book, written by respected experts, discusses in detail the latest developments in targeted therapy for hematologic malignancies using small molecules. It covers a wide range of small molecules including tyrosine kinase inhibitors, immunomodulatory drugs, the IDH-2 inhibitor enasidenib, the BCL-2 inhibitor venetoclax, and the proteasome inhibitor carfilzomib. For each molecule, aspects such as the chemical  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Small molecules in hematology.
Cham, Switzerland : Springer, 2018
(OCoLC)1031341546
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Uwe M Martens
ISBN: 9783319914398 3319914391 9783319914404 3319914405
OCLC Number: 1047729250
Description: 1 online resource
Contents: Imatinib Mesylate --
Dasatinib --
Nilotinib --
Bosutinib: a potent second-generation tyrosine kinase inhibitor --
Ponatinib: a third-generation inhibitor for the treatment of CML --
Ruxolitinib --
Ibrutinib --
Pomalidomide --
Enasidenib --
Midostaurin: a multiple kinases inhibitor in acute myeloid leukemia and systemic mastocytosis --
Venetoclax: targeting BCL2 in hematological cancers --
Idelalisib --
Carfilzomib --
Acalabrutinib, a second-generation Bruton's tyrosine kinase inhibitor.
Series Title: Recent results in cancer research, v. 212.
Responsibility: Uwe M. Martens, editor.

Abstract:

It covers a wide range of small molecules including tyrosine kinase inhibitors, immunomodulatory drugs, the IDH-2 inhibitor enasidenib, the BCL-2 inhibitor venetoclax, and the proteasome inhibitor  Read more...

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