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Solvent systems and their selection in pharmaceutics and biopharmaceutics

Author: Patrick Augustijns; Marcus Brewster; American Association of Pharmaceutical Scientists.
Publisher: New York, NY : Springer/AAPS Press, 2007.
Series: Biotechnology (Arlington, Va.), v. 6.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Publication:Springer e-books
Summary:
Solvent systems are integral to drug development and pharmaceutical technology. This single topic encompasses numerous allied subjects running the gamut from recrystallization solvents to biorelevant media. The goal of this contribution to the AAPS Biotechnology: Pharmaceutical Aspects series is to generate both a practical handbook as well as a reference allowing the reader to make effective decisions concerning  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Solvent systems and their selection in pharmaceutics and biopharmaceutics.
New York, NY : Springer/AAPS Press, 2007
(DLC) 2007924356
(OCoLC)123374507
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Patrick Augustijns; Marcus Brewster; American Association of Pharmaceutical Scientists.
ISBN: 9780387691541 0387691545 9780387691497 0387691499
OCLC Number: 191449547
Description: 1 online resource (viii, 459 pages) : illustrations.
Contents: Principles of Solubility --
Ionic Equilibria and the pH Dependence of Solubility --
Solvent Systems for Crystallization and Polymorph Selection --
Solubility Issues in Early Discovery and HTS --
Practical Aspects of Solubility Determination in Pharmaceutical Preformulation --
Biorelevant Dissolution Media --
Selection of Solvent Systems for Membrane-, Cell- and Tissue-Based Permeability Assessment --
The Use of Solubilizing Excipients and Approaches to Generate Toxicology Vehicles for Contemporary Drug Pipelines --
Solubilizing Vehicles for Oral Formulation Development --
Solubilizing Systems for Parenteral Formulation Development--Small Molecules --
Aqueous Solubilizing Systems for Parenteral Formulation Development--Proteins --
Non-Aqueous Systems for Formulation Development--Proteins --
Pharmaceutical Solvents as Vehicles for Topical Dosage Forms --
Pharmaceutical Solvents for Pulmonary Drug Delivery.
Series Title: Biotechnology (Arlington, Va.), v. 6.
Responsibility: [edited by] Patrick Augustijns, Marcus Brewster.
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