Sterile dosage forms. (Book, 1994) [WorldCat.org]
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Sterile dosage forms.
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Sterile dosage forms.

Author: Salvatore J Turco
Publisher: Philadelphia ; London : Lea & Febiger, 1994.
Edition/Format:   Print book : English : 4th edView all editions and formats
Summary:

Narrows the gap between those who manufacture and those who routinely prepare, dispense and administer parenteral drugs, by giving each group an appreciation of what the other must accomplish to  Read more...

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Document Type: Book
All Authors / Contributors: Salvatore J Turco
ISBN: 0812116178 9780812116175
OCLC Number: 30029515
Description: xii, 519 pages
Contents: Part 1: history of parenteral medication; development of parenteral packaging; development of routes of administration; advantages of parenteral administration; disadvantages of parenteral adminstration. Part 2: composition; types of preparations; vehicles; added substances for parenterals; added substances for sterile suspensions; added substances for ophthalmic solutions. Part 3 characteristics; sterility; freedom from particulate matters; freedom from pyrogens; stability. Part 4: large scale preparation; environmental control; personnel; packaging components; preparation for packaging components; preparation on product; control; labelling. Part 5: extemporaneous preparation; parenteral manufacturing in hospitals; environmental control; personnel; packaging components; injections; subdivision of solution; sterile solids; sterile suspensions; quality control. Part 6: handling and administration, Faye Consentino; the patient; personnel administering parenteral drugs; techniques of parenteral adminstration; intermittent intravenous therapy; initiating and maintaining an intravenous system; complications of intravenous therapy. Part 7: biopharmaceutic factors influencing drug availability; physicochemical influences on bioavailability; physiologic factors influencing drug absorption; dosage form considerations; drug absorption and bioavailability from intramuscular injection; drug absorption from subcutaneous injection; biopharmaceutics of intrathecal injections; parenteral administration of peptides and proteins; parenteral drug delivery systems. Part 8: large-volume sterile solutions; large-volume solutions for intravenous use; large-volume solutions not administered intravenously; intravenous fluid administration systems; storage of intravenous fluids; methods of intravenous administration; flow rates of intravenous infusion fluids; flow control in I.V. therapy; selection of infusion devices; justification for infusion devices; committee for instrument selection; criteria for using infusion devices; standardized concentration for drugs administered by constant infusion; mechanical controlling devices; recommendations for infusion devices; patient-controlled analgesia (PCA); future trends for infusion devices; plastic medical components; I.V. terms; national co-ordinating committee on large volume parenterals; trends and developments in I.V. delivery systems; large-volume parenterals (LVPs) with manufactured additives (premixes); mini-infuser pumps for intermittent I.V. drug delivery. (Part contents).

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