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The story of taxol : nature and politics in the pursuit of an anti-cancer drug

Author: Jordan Goodman; Vivien Walsh
Publisher: Cambridge ; New York : Cambridge University Press, 2001.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
"Taxol is arguably the most celebrated, talked about, and controversial natural product in recent years: Celebrated because of its efficacy as an anti-cancer drug and because its discovery has provided powerful support for policies concerned with biodiversity. Talked about because in the late 1980s and early 1990s, the American public was bombarded with news reports about the molecule and its host, the slow-growing  Read more...
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Genre/Form: Student Collection
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Jordan Goodman; Vivien Walsh
ISBN: 052156123X 9780521561235
OCLC Number: 44117896
Description: xiii, 282 pages : illustrations ; 24 cm
Contents: pt. I. Agents. Cancer chemotherapy: plant knowledge and practice --
pt. II. Practices. Act I: 1962-1975 --
Act II: 1976-1983 --
Act III: 1984-1989 --
pt. III. Controversies. The politics of exclusivity and the business of taxol --
The political life (and death) of Taxus brevifolia.
Responsibility: Jordan Goodman, Vivien Walsh.
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Abstract:

During the late 1980s and early 1990s, taxol was hailed for its efficacy as an anti-cancer drug while becoming embroiled in a number of political issues with wide policy implications. This book tells  Read more...

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'It is carefully researched and detailed, and as someone who was at the National Cancer Institute (NCI) during part of the development of Taxol, I found it factually accurate.' Vincent T. DeVita, Jr, Read more...

 
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    schema:reviewBody ""Taxol is arguably the most celebrated, talked about, and controversial natural product in recent years: Celebrated because of its efficacy as an anti-cancer drug and because its discovery has provided powerful support for policies concerned with biodiversity. Talked about because in the late 1980s and early 1990s, the American public was bombarded with news reports about the molecule and its host, the slow-growing Pacific yew. Controversial because the drug and the tree became embroiled in several sensitive political issues with broad public policy implications." "Taxol has revolutionized the treatment options for patients with advanced forms of breast and ovarian cancers and some types of leukemia; it shows promise for treating AIDS-related Kaposi's sarcoma. It is the best-selling anti-cancer drug ever, with world sales of $1.2 billion in 1998 and expected to grow. Goodman and Walsh's careful study of how taxol was discovered, researched, and brought to market documents the complexities and conflicting interests in the ongoing process to find effective treatments. From a broader perspective, The Story of Taxol uses the discovery and development of taxol as a paradigm to address current issues in the history and sociology of science and medicine."--Jacket." ;
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