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Stress-inducible cellular responses

Author: U Feige, Dr.
Publisher: Basel ; Boston : Birkhäuser Verlag, ©1996.
Series: EXS, 77.
Edition/Format:  eBook : Document : EnglishView all editions and formats
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Genre/Form: Electronic books
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: U Feige, Dr.
ISBN: 3764352051 9783764352059 0817652051 9780817652050
OCLC Number: 1012436800
Description: 1 online resource
Contents: I: Functions of stress proteins in unstressed cells --
Normal protein folding machinery --
Roles for hsp70 in protein translocation across membranes of organelles --
Protein folding and assembly in the endoplasmic reticulum --
Involvement of molecular chaperones in intracellular protein breakdown --
Molecular chaperoning of steroid hormone receptors --
Protein disulfide isomerase: A multifunctional protein of the endoplasmic reticulum --
II: Regulation of inducible stress responses --
Sensing stress and responding to stress --
The transcriptional regulation of heat shock genes: A plethora of heat shock factors and regulatory conditions --
Transcriptional regulation of stress-inducible genes in procaryotes --
The impact of oxidative stress on eukaryotic iron metabolism --
Heat-shock induced protein modifications and modulation of enzyme activities --
SOS response as an adaptive response to DNA damage in prokaryotes --
III: Cellular responses to specific stresses --
Transcriptional regulators of oxidative stress-inducible genes in prokaryotes and eukaryotes --
UV activation of mammalian stress proteins --
Signaling events controlling the molecular response to genotoxic stress --
Mammalian DNA repair responses and genomic instability --
Toxic metal-responsive gene transcription --
Tumor necrosis factor and lymphotoxin: Protection against oxidative stress through induction of MnSOD --
IV: Paradigms for complex stress responses --
Viral infection --
Infection, autoimmunity and autoimmune disease --
Stress proteins in inflammation --
Attenuated heat shock transcriptional response in aging: Molecular mechanism and implication in the biology of aging --
V: Applications of stress responses in toxicology and pharmacology --
Stress proteins as molecular biomarkers for environmental toxicology --
Thermotolerance and heat shock proteins: Possible involvement of Ku autoantigen in regulating HSP70 expression --
Heat shock proteins as immunological carriers and vaccines --
Regulation of thermotolerance and ischemic tolerance --
Future applications --
Outlook.
Series Title: EXS, 77.
Responsibility: edited by U. Feige [and others].

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