Find a copy in the library
Finding libraries that hold this item...
Details
Document Type: | Book |
---|---|
All Authors / Contributors: |
Saša Jenko; Dušan Turk |
OCLC Number: | 456317825 |
Description: | 44 f. : ilustr., tabele ; 30 cm |
Responsibility: | Saša Jenko. |
Abstract:
The crystal structure of porcine cathepsin H in complex with recombinant humanstefin A reveals the exopeptidase - inhibitor interaction. The Nterminal of stefin A cannot bind into the active site of cathepsin H with the same geometry as the N-terminal of stefin B in the complex with papain due to steric hindrance. It makes a beta turn and points with the Nterminal residue away from the active site cleft. C-terminal part of minichain of cathepsin H and a short insertion loop Lys155A-Asp155D are thereby displaced, their geometry appears to be disordered.
Reviews
User-contributed reviews
Add a review and share your thoughts with other readers.
Be the first.
Add a review and share your thoughts with other readers.
Be the first.


Tags
Add tags for "Strukturne študije kompleksov katepsinov s proteinskimi inhibitorji".
Be the first.
Similar Items
Related Subjects:(9)
- Cathepsins -- ultrastructure.
- Cystatins -- antagonists & inhibitors.
- Cystatins -- chemical synthesis.
- Peptide hydrolases -- chemical syntesis.
- Katepsini -- Ultrastruktura.
- Cistatini -- Antagonisti in inhibitorji.
- Cistatini -- Kemična sinteza.
- Peptidne hidrolaze -- Kemična sinteza.
- biokemija -- molekularna biologija