System modeling in cell biology : from concepts to nuts and bolts (eBook, 2010) [WorldCat.org]
skip to content
System modeling in cell biology : from concepts to nuts and bolts Preview this item
ClosePreview this item
Checking...

System modeling in cell biology : from concepts to nuts and bolts

Author: Zoltan Szallasi; Jörg Stelling; Vipul Periwal
Publisher: Cambridge, Mass. ; London : MIT Press, ©2006.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Research in systems biology requires the collaboration of researchers from diverse backgrounds, including biology, computer science, mathematics, statistics, physics, and biochemistry. These collaborations, necessary because of the enormous breadth of background needed for research in this field, can be hindered by differing understandings of the limitations and applicability of techniques and concerns from  Read more...
Rating:

(not yet rated) 0 with reviews - Be the first.

Subjects
More like this

Find a copy in the library

&AllPage.SpinnerRetrieving; Finding libraries that hold this item...

Details

Genre/Form: Electronic books
Material Type: Document
Document Type: Book, Computer File
All Authors / Contributors: Zoltan Szallasi; Jörg Stelling; Vipul Periwal
ISBN: 0262257068 9780262257060 1282096796 9781282096790 9786612096792 6612096799 1423772547 9781423772545 9780262195485 0262195488
OCLC Number: 1059033306
Language Note: English.
Notes: Description based upon print version of record.
Description: 1 online resource (465 p.)
Contents: Preface; I GENERAL CONCEPTS; 1 The Role of Modeling in Systems Biology; 2 Complexity and Robustness of Cellular Systems; 3 On Modules and Modularity; II MODELING APPROACHES; 4 Bayesian Inference of Biological Systems: The Logic of Biology; 5 Stoichiometric and Constraint-based Modeling; 6 Modeling Molecular Interaction Networks with Nonlinear Ordinary Differential Equations; 7 Qualitative Approaches to the Analysis of Genetic Regulatory Networks; 8 Stochastic Modeling of Intracellular Kinetics; 9 Kinetics in Spatially Extended Systems; III MODELS AND REALITY. 10 Biological Data Acquisition for System Level Modeling-An Exercise in the Art of Compromise11 Methods to Identify Cellular Architecture and Dynamics from Experimental Data; 12 Using Control Theory to Study Biology*; 13 Synthetic Gene Regulatory Systems; 14 Multilevel Modeling in Systems Biology: From Cells to Whole Organs; IV COMPUTATIONAL MODELING; 15 Computational Constraints on Modeling in Systems Biology; 16 Numerical Simulation for Biochemical Kinetics; 17 Software Infrastructure for Effective Communication and Reuse of Computational Models; A Software Tools for Biological Modeling.
Other Titles: System Modeling in Cellular Biology: From Concepts to Nuts and Bolts
System Modeling in Cell Biology :
Responsibility: edited by Zoltan Szallasi, Jörg Stelling, Vipul Periwal.
More information:

Abstract:

Research in systems biology requires the collaboration of researchers from diverse backgrounds, including biology, computer science, mathematics, statistics, physics, and biochemistry. These collaborations, necessary because of the enormous breadth of background needed for research in this field, can be hindered by differing understandings of the limitations and applicability of techniques and concerns from different disciplines. This comprehensive introduction and overview of system modeling in biology makes the relevant background material from all pertinent fields accessible to researchers with different backgrounds.The emerging area of systems level modeling in cellular biology has lacked a critical and thorough overview. This book fills that gap. It is the first to provide the necessary critical comparison of concepts and approaches, with an emphasis on their possible applications. It presents key concepts and their theoretical background, including the concepts of robustness and modularity and their exploitation to study biological systems; the best-known modeling approaches, and their advantages and disadvantages; lessons from the application of mathematical models to the study of cellular biology; and available modeling tools and datasets, along with their computational limitations.

Reviews

User-contributed reviews
Retrieving GoodReads reviews...
Retrieving DOGObooks reviews...

Tags

Be the first.
Confirm this request

You may have already requested this item. Please select Ok if you would like to proceed with this request anyway.

Close Window

Please sign in to WorldCat 

Don't have an account? You can easily create a free account.