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Systems Biology : the Challenge of Complexity

Author: Shigetada Nakanishi; Ryoichiro Kageyama; Dai Watanabe
Publisher: Tokyo : Springer Japan, 2009.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:

Instead of reductionistic analyses or large-scale studies of biomolecules piece by piece, systems biology emphasizes the need for interdisciplinary methods and analysis of the regulation and  Read more...

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Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Shigetada Nakanishi; Ryoichiro Kageyama; Dai Watanabe
ISBN: 9784431877035 4431877037 9784431877042 4431877045
OCLC Number: 1012508836
Description: 1 online resource
Contents: Dynamics and Complexity of Intercellular Networks.- Integrative Synaptic Mechanisms of the Neural Network.- The Molecular and Cellular Design of Networks in Motion.- Bacterial Complexity: More Is Different on All Levels.- How Animals Get Their Skin Patterns: Fish Pigment Pattern as a Live Turing Wave.- Characterization and Application of Natural Light-Sensitive Proteins.- Systems Biology of Mammalian Circadian Clocks.- Toward Understanding How the Immune System Establishes a Diverse Yet Self-Tolerant T-Cell Repertoire: Stepwise Roles of Thymic Microenvironments.- The Mechanisms of Motor Programming for Learned Vocalization in Songbirds.- Dynamic Model of the Basal Ganglia Functions and Movement Disorders.- Integrative Mechanism of Intracellular Information Networks.- A Posttranslational Chemical Circadian Oscillator in Cyanobacteria.- The Apoptotic Signaling Network Dynamically Interprets the Outputs of Individual Signaling Pathways in an Early Analog and Late Digital Manner.- Specific Features of Transient Ras and Sustained Rap1 Activation.- Control and Alteration of Protein Traffic in the Cell.- Plant Functional Genomics Based on Integration of Metabolomics and Transcriptomics: Toward Plant Systems Biology.- A Possible Role of Homeostasis Between Monomeric and Filamentous Actin in Filament Nucleation Revealed by Pharmacokinetic Modeling.- Molecules, Networks, and Memory.- Systems Biology Meets Single-Cell Physiology: Role of a Positive-Feedback Signal Transduction Network in Cerebellar Long-Term Synaptic Depression.- Computational Models of Cerebellar Long-Term Memory.- Biogenesis and Function Mechanisms of Micro-RNAs and Their Role as Oncogenes and Tumor Suppressors.- Dysfunction of Information Networks and Related Diseases.- The Pathogenetic Significance of Deregulated Transcription Factors in Hematological Malignancies.- Ultradian Oscillation Networks in Somite Segmentation and Other Biological Events.- The Cellular Basis of Dictyostelium Morphogenesis.- Metabolic Information Highway: Interorgan Metabolic Communication Via the Autonomic Nervous System.- Involvement of the CCR4-NOT Deadenylase Complex in the Control of Cell Growth.- Reconstruction of Nuclear Reprogramming by Defined Factors.
Responsibility: edited by Shigetada Nakanishi, Ryoichiro Kageyama, Dai Watanabe.

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