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TCTP/Tpt1 : remodeling signaling from stem cell to disease

Author: Adam Telerman; Robert Amson
Publisher: Cham, Switzerland : Springer, [2017]
Series: Results and problems in cell differentiation, 64.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
This book highlights the role of the Translationally Controlled Tumor Protein (TCTP) in cell signaling, cell fate and the resulting connection to disease development. It begins by discussing the structure/function of TCTP, before exploring its role in different species ranging from plants to Drosophila and covering fields such as development, the cytoskeleton, cell division, DNA fragility and apoptosis. In turn, the  Read more...
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Genre/Form: Electronic book
Electronic books
Additional Physical Format: Print version:
Telerman, Adam.
TCTP/tpt1 - Remodeling Signaling from Stem Cell to Disease.
Cham : Springer International Publishing, ©2017
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Adam Telerman; Robert Amson
ISBN: 9783319675916 3319675915 3319675907 9783319675909
OCLC Number: 1012882139
Description: 1 online resource
Contents: 1 Introduction: How we encountered TCTP and our purpose in studying it --
2 Structural insights into TCTP and its interactions with ligands and proteins --
3 Structure-Function relationship of TCTP --
4 The Translational Controlled Tumour Protein TCTP: Biological Functions and Regulation --
5 Current understanding of the TCTP interactome --
6 Role and fate of TCTP in protein degradative pathways --
7 Roles of the Translationally Controlled Tumor Protein (TCTP) in plant development --
8 Function of Translationally controlled tumor protein in organ growth: Lessons from Drosophila studies --
9 Translationally controlled tumor protein (TCTP/HRF) present in animal venoms --
10 Tctp in Neuronal Circuitry Assembly --
11 Elusive role of TCTP protein and mRNA in cell cycle and cytoskeleton regulation --
12 TCTP protein and the cellular response to ionizing radiation-induced DNA damage --
13 TCTP has a crucial role in the different stages of Prostate Cancer malignant progression --
14 Role of TCTP for cellular differentiation and cancer therapy --
15 Targeting TCTP with sertraline and thioridazine in cancer treatment --
16 . History of Histamine Releasing Factor (HRF)/TCTP including a Potential Therapeutic Target in Asthma and Allergy.
Series Title: Results and problems in cell differentiation, 64.
Responsibility: Adam Telerman, Robert Amson, editors.

Abstract:

This book highlights the role of the Translationally Controlled Tumor Protein (TCTP) in cell signaling, cell fate and the resulting connection to disease development.  Read more...

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<http:\/\/experiment.worldcat.org\/entity\/work\/data\/4627308464#Person\/telerman_adam<\/a>> # Adam Telerman<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Person<\/a> ;\u00A0\u00A0\u00A0\nschema:familyName<\/a> \"Telerman<\/span>\" ;\u00A0\u00A0\u00A0\nschema:givenName<\/a> \"Adam<\/span>\" ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Adam Telerman<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
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