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Therapeutic intranasal delivery for stroke and neurological disorders

Author: Jun Chen, (Professor of neurology and pharmacology); Jian Wang; Ling Wei; J H Zhang
Publisher: Cham : Springer, 2019.
Series: Springer series in translational stroke research.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
The blood-brain-barrier prevented harmful materials entering the brain and in the meantime is a barricade to therapeutic drug delivery. Intranasal drug delivery to circumvent blood-brain-barrier was developed in the past, to take advantages of a secret passage from the olfactory epithelium into the brain-bypassing the tight junctions that encapsulated the brain from blood circulation. This timely publication of  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Printed edition:
Printed edition:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Jun Chen, (Professor of neurology and pharmacology); Jian Wang; Ling Wei; J H Zhang
ISBN: 9783030167158 3030167151 3030167135 9783030167134 9783030167141 3030167143
OCLC Number: 1103605874
Description: 1 online resource
Contents: Preface --
Transnasal Induction of Therapeutic Hypothermia for Neuroprotection --
Hypoxia-Primed Stem Cell Transplantation in Stroke --
Therapeutic potential of intranasal drug delivery in preclinical studies of ischemic stroke and intracerebral hemorrhage --
Intranasal Drug Delivery after Intracerebral Hemorrhage --
Intranasal Treatment in Subarachnoid Hemorrhage --
Intranasal Delivery of Therapeutic Peptides for Treatment of Ischemic Brain Injury --
Intranasal delivering method in the treatment of ischemic stroke --
Intranasal Delivery of Drugs for Ischemic Stroke Treatment: Targeting IL-17A --
Intranasal tPA application for axonal remodeling in rodent stroke and traumatic brain injury models --
Therapeutic Intranasal Delivery for Alzheimer's disease --
Combination therapy of intranasal IGF-1 and hypothermia --
Intranasal Medication Delivery in Children for Brain Disorders --
Index.
Series Title: Springer series in translational stroke research.
Responsibility: Jun Chen, Jiang Wang, Ling Wei, John H. Zhang, editors.

Abstract:

In the last 10 years, intranasal delivery of various therapeutic compounds including small chemicals, large proteins, and even stem cells has proven to be very effective in bypassing the  Read more...

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