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Toward a molecular basis of alcohol use and abuse

Author: Bengt Jansson
Publisher: Basel ; Boston : Birkhäuser Verlag, ©1994.
Series: EXS, 71.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
The chapters in this volume consider subjects ranging from genetics, markers, and molecular biology of alcoholism, to clinical observations and treatment. The aim is to integrate pertinent information from the fields of molecular and cell biology with clinical and pharmacological knowledge in the attempt to establish molecular bases of alcohol use and abuse. An introductory section summarizes historical aspects of  Read more...
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Additional Physical Format: Online version:
Toward a molecular basis of alcohol use and abuse.
Basel ; Boston : Birkhäuser Verlag, ©1994
(OCoLC)609187618
Online version:
Toward a molecular basis of alcohol use and abuse.
Basel ; Boston : Birkhäuser Verlag, ©1994
(OCoLC)624443942
Document Type: Book
All Authors / Contributors: Bengt Jansson
ISBN: 3764329408 9783764329402 0817629408 9780817629403
OCLC Number: 30030941
Description: x, 407 pages : illustrations (some color) ; 24 cm.
Contents: Alcohol in human history / B.L. Vallee --
Reward and its control by dynorphin peptides / L. Terenius --
Adaptation of signal transduction in brain / C. Alling, L. Gustavsson, C. Larsson, C. Lundqvist, D. Rodriguez and P. Simonsson --
Protein kinase C and adaptation to ethanol / R. Roivainen, B. Hundle and R.O. Messing --
Molecular control of neuronal survival in the chick embryo / S. Biffo, G. Dechant, H. Okazawa and Y.-A. Barde --
Effects of alcohol on gene expression in neural cells / N. Wilke, M. Sganga, S. Barhite and M.F. Miles --
The role of the NMDA receptor in ethanol withdrawal / P.L. Hoffman and B. Tabakoff --
Molecular diversity of glutamate receptors and their physiological functions / S. Nakanishi, M. Masu, Y. Bessho, Y. Nakajima, Y. Hayashi and R. Shigemoto --
Multiple dopamine receptors: The D[subscript 3] receptor and actions of substances of abuse / J.-C. Schwartz, J. Diaz, N. Griffon, D. Levesque, M.-P. Martres and P. Sokoloff. Molecular pharmacology of serotonin receptors / P.R. Hartig --
Alcohol, the reward system and dependence / G.F. Koob, S. Rassnick, S. Heinrichs and F. Weiss --
Clinical aspects on molecular probes, markers and metabolism / U. Rydberg --
Familial alcoholism: Family, twin adoption and high risk studies / J. Knop --
Association strategies in substance abuse / G.R. Uhl --
PET-determination of benzodiazepine receptor binding in studies on alcoholism / L. Farde, S. Pauli, J.-E. Litton, C. Halldin, J. Neiman and G. Sedvall --
Serotonin, violent behavior and alcohol / M. Linnoila, M. Virkkunen, T. George, M. Eckardt, J.D. Higley, D. Nielsen and D. Goldman --
Neuropeptides and alcohol addiction in monkeys / J.M. van Ree, M. Kornet and C. Goosen --
The role of adenosine in mediating cellular and molecular responses to ethanol / I. Diamond and A.S. Gordon --
Helicobacter pylori alcohol dehydrogenase / M. Salaspuro. Genetic polymorphism of cytochrome P450. Functional consequences and possible relationship to disease and alcohol toxicity / M. Ingelman-Sundberg, I. Johansson, I. Persson, M. Oscarson, Y. Hu, L. Bertilsson, M.-L. Dahl and F. Sjoqvist --
Serotonin-altering medications and desire, consumption and effects of alcohol-treatment implications / C.A. Naranjo and K.E. Bremner --
The alcohol dehydrogenase system / H. Jornvall --
Drug metabolism and signal transduction: Possible role of Ah receptor and arachidonic acid cascade in protection from ethanol toxicity / D.W. Nebert --
Recruitment of enzymes and stress proteins as lens crystallins / J. Piatigorsky, M. Kantorow, R. Gopal-Srivastava and S.I. Tomarev --
X-ray structure of PQQ-dependent methanol dehydrogenase / M. Ghosh, A. Avezoux, C. Anthony, K. Harlos and C.C.F. Blake --
NMR, alcohols, protein solvation and protein denaturation / K. Wuthrich. Crystallographic investigations of alcohol dehydrogenases / H. Eklund, S. Ramaswamy, B.V. Plapp, M. El-Ahmad, O. Danielsson, J.-O. Hoog and H. Jornvall --
Retinoids and the alcohol dehydrogenase gene family / G. Duester --
Alcohol and acetaldehyde dehydrogenase gene polymorphism and alcoholism / D.I.N. Sherman, R.J. Ward, A. Yoshida and T.J. Peters --
Site-directed mutagenesis and enzyme properties of mammalian alcohol dehydrogenases correlated with their tissue distribution / J.-O. Hoog, M. Estonius and O. Danielsson --
Control of alcohol metabolism / B.V. Plapp --
Angiotensin converting enzyme inhibitors and alcohol abuse / J.F. Riordan --
Treatment of alcoholism / B. Jansson --
Alcohol sensitivity and dependence / M.A. Schuckit --
Treatment of alcoholism as a chronic disorder / C.P. O'Brien --
Addiction and the potential for therapeutic drug development / P.A.J. Janssen. Therapeutic lessons from traditional Oriental medicine to contemporary Occidental pharmacology / W.-M. Keung and B.L. Vallee --
Potential gene therapy for alcoholism / R.O. Brady --
Outlook: Prospects for alcoholism treatment / E. Gordis.
Series Title: EXS, 71.
Responsibility: edited by B. Jansson [and others].

Abstract:

The 39 chapters in this volume consider subjects ranging from genetics, markers, and molecular biology of alcoholism, to clinical observations and treatment. The aim is to integrate pertinent  Read more...

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