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Tumor immune microenvironment in cancer progression and cancer therapy

Author: Pawel Kalinski
Publisher: Cham, Switzerland : Springer, 2017.
Series: Advances in experimental medicine and biology, v. 1036.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
The tumor microenvironment has become a very important and hot topic in cancer research within the past few years. The tumor microenvironment is defined as the normal cells, molecules, and blood vessels that surround and feed a tumor cell. As many scientists have realized, studying the tumor microenvironment has become critical to moving the field forward, since there are many players in a tumor?s localized and  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Printed edition:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Pawel Kalinski
ISBN: 9783319675770 331967577X 3319675753 9783319675756
OCLC Number: 1017489272
Description: 1 online resource
Contents: Part 1. Interplay Between Tumor Cells, Stroma and Inflammatory Infiltrate in Regulating Tumor Micro-Environment --
Tumor Immuno-Environment in Cancer Progression and Therapy --
Cancer Immunotherapy Targets Based on Understanding the T Cell-Inflamed Versus Non-T Cell-Inflamed Tumor Microenvironment --
Regulation of CTL Infiltration Within the Tumor Microenvironment --
The Role of Tumor Microenvironment in Cancer Immunotherapy --
Part 2. Mediators of Tumor Microenvironment --
Immunogenic and Non-Immunogenic Cell Death in the Tumor Microenvironment --
Exosomes in Cancer: Another Mechanism of Tumor-Induced Immune Suppression --
Chemo-immunotherapy: Impact of Indoleamine 2,3-dioxygenase in Defining Immunogenic versus Tolerogenic Cell Death in the Tumor Microenvironment --
Targeting Myeloid-Derived Suppressor Cells in Cancer --
Tryptophan catabolism and cancer immunotherapy targeting IDO mediated immune Suppression --
Part 3. Emerging Targets and Technologies of Modulation of Tumor Microenvironment --
Tumor Microenvironment in Cancer Progression and Therapy --
The Role of the Immune System and Immunoregulatory Mechanisms Relevant to Melanoma --
Oncolytic Virotherapy and the Tumor Microenvironment --
The Impact of Housing Temperature Induced Chronic Stress on Preclinical Mouse Tumor Models and Therapeutic Responses: An Important Role for the Nervous Role for the Nervous System --
(Immuno)therapeutic Targeting of Tumor-Associated Blood Vessels --
Adaptive Resistance to Cancer Immunotherapy --
Imaging the Tumor Microenvironment.
Series Title: Advances in experimental medicine and biology, v. 1036.
Responsibility: Pawel Kalinski, editor.

Abstract:

Recent studies have demonstrated that in addition to promoting tumor progression and protecting tumor cells from the spontaneous immune-mediated rejection and different forms of cancer therapeutics,  Read more...

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