skip to content
Tumor suppressor genes. Volume 1, Pathways and isolation strategies Preview this item
ClosePreview this item
Checking...

Tumor suppressor genes. Volume 1, Pathways and isolation strategies

Author: Wafik S El-Deiry
Publisher: Totowa, N.J. ; [Great Britain] : Humana Press, ©2003.
Series: Methods in molecular biology (Clifton, N.J.), v. 222.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Powerful new tools are now available to discover and understand tumor suppressor genes (TSGs) and the biochemical mechanisms by which they control cancer development and progression. In Tumor Suppressor Genes, Volume 1: Pathways and Isolation Strategies, leading physician scientists and academic researchers review all the known tumor suppressor genes, explain how they work, and describe how they were discovered and  Read more...
Rating:

(not yet rated) 0 with reviews - Be the first.

Subjects
More like this

Find a copy online

Links to this item

Find a copy in the library

&AllPage.SpinnerRetrieving; Finding libraries that hold this item...

Details

Genre/Form: Electronic books
Laboratory manuals
Additional Physical Format: Print version:
Tumor suppressor genes. Volume 1, Pathways and isolation strategies.
Totowa, N.J. ; [Great Britain] : Humana Press, ©2003
(DLC) 2002027501
(OCoLC)52288595
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Wafik S El-Deiry
ISBN: 9781592593286 1592593283 9780896039865 0896039862
OCLC Number: 170622033
Description: 1 online resource (1 volume) : illustrations
Contents: Known Tumor Suppessor Genes and Pathways --
Growth Control by the Retinoblastoma Gene Family --
The APC Tumor Suppressor Pathway --
Hereditary Breast and Ovarian Cancer Genes --
Hereditary Colon Cancer Genes --
Patched, Hedgehog, and Skin Cancer --
Tumor Suppressor Genes in Lung Cancer --
TP53, hChk2, and the Li-Fraumeni Syndrome --
Genetic Alterations in Esophageal Cancer --
PTEN and Cancer --
VHL and Kidney Cancer --
p16INK4A and Familial Melanoma --
The INK4a/ARF Locus and Human Cancer --
Progression Model of Prostate Cancer --
Neurofibromatosis Type 1 --
Wilms' Tumor as a Model for Cancer Biology --
Inadequate "Caretaker" Gene Function and Human Cancer Development --
The Regulation of Tumor Suppressor Genes by Oncogenes --
Identification of Tumor Suppressor Genes --
Determination of Cancer Allelotype --
Epidemiological Approaches to the Identification of Cancer Predisposition Genes --
Characterization of Translocations in Human Cancer --
Positional Approaches to Cancer Genetics --
Hybrid Capture of Putative Tumor Suppressor Genes --
Approaches to Proteomic Analysis of Human Tumors --
Representational Difference Analysis of Gene Expression --
Antisense Libraries to Isolate Tumor Suppressor Genes --
Genetic Suppressor Elements in the Characterization and Identification of Tumor Suppressor Genes --
Cross-linking Subtractive Hybridization to Identify Tumor Suppressor Genes --
Suppression Subtractive Hybridization for Identification and Functional Analysis of Tumor Suppressor Genes --
SAGE as a Strategy to Isolate Cancer-Related Genes --
Differential Display Techniques to Identify Tumor Suppressor Gene Pathways --
Detection of Mismatch Repair Gene Expression in Urologic Malignancies.
Series Title: Methods in molecular biology (Clifton, N.J.), v. 222.
Responsibility: edited by Wafik S. El-Deiry.

Abstract:

It has become clear that tumors arise from excessive cell proliferation and a c- responding reduction in cell death. The signaling pathways controlled by these genes involve virtually every process  Read more...

Reviews

User-contributed reviews
Retrieving GoodReads reviews...
Retrieving DOGObooks reviews...

Tags

Be the first.
Confirm this request

You may have already requested this item. Please select Ok if you would like to proceed with this request anyway.

Linked Data


\n\n

Primary Entity<\/h3>\n
<http:\/\/www.worldcat.org\/oclc\/170622033<\/a>> # Tumor suppressor genes. Volume 1, Pathways and isolation strategies<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:CreativeWork<\/a>, schema:MediaObject<\/a>, schema:Book<\/a> ;\u00A0\u00A0\u00A0\nlibrary:oclcnum<\/a> \"170622033<\/span>\" ;\u00A0\u00A0\u00A0\nlibrary:placeOfPublication<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/2796866662#Place\/totowa_n_j<\/a>> ; # Totowa, N.J.<\/span>\n\u00A0\u00A0\u00A0\nlibrary:placeOfPublication<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/2796866662#Place\/great_britain<\/a>> ; # Great Britain<\/span>\n\u00A0\u00A0\u00A0\nlibrary:placeOfPublication<\/a> <http:\/\/id.loc.gov\/vocabulary\/countries\/nju<\/a>> ;\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/2796866662#Topic\/health_&_fitness_diseases_cancer<\/a>> ; # HEALTH & FITNESS--Diseases--Cancer<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/dewey.info\/class\/616.994042\/e22\/<\/a>> ;\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/2796866662#Topic\/genes_tumor_suppressor<\/a>> ; # Genes, Tumor Suppressor<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/2796866662#Topic\/medical_oncology<\/a>> ; # MEDICAL--Oncology<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/id.loc.gov\/authorities\/subjects\/sh90002154<\/a>> ; # Antioncogenes<\/span>\n\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/2796866662#Topic\/antioncogenes<\/a>> ; # Antioncogenes<\/span>\n\u00A0\u00A0\u00A0\nschema:bookFormat<\/a> schema:EBook<\/a> ;\u00A0\u00A0\u00A0\nschema:contributor<\/a> <http:\/\/viaf.org\/viaf\/74109351<\/a>> ; # Wafik S. El-Deiry<\/span>\n\u00A0\u00A0\u00A0\nschema:copyrightYear<\/a> \"2003<\/span>\" ;\u00A0\u00A0\u00A0\nschema:datePublished<\/a> \"2003<\/span>\" ;\u00A0\u00A0\u00A0\nschema:description<\/a> \"Known Tumor Suppessor Genes and Pathways -- Growth Control by the Retinoblastoma Gene Family -- The APC Tumor Suppressor Pathway -- Hereditary Breast and Ovarian Cancer Genes -- Hereditary Colon Cancer Genes -- Patched, Hedgehog, and Skin Cancer -- Tumor Suppressor Genes in Lung Cancer -- TP53, hChk2, and the Li-Fraumeni Syndrome -- Genetic Alterations in Esophageal Cancer -- PTEN and Cancer -- VHL and Kidney Cancer -- p16INK4A and Familial Melanoma -- The INK4a\/ARF Locus and Human Cancer -- Progression Model of Prostate Cancer -- Neurofibromatosis Type 1 -- Wilms\' Tumor as a Model for Cancer Biology -- Inadequate \"Caretaker\" Gene Function and Human Cancer Development -- The Regulation of Tumor Suppressor Genes by Oncogenes -- Identification of Tumor Suppressor Genes -- Determination of Cancer Allelotype -- Epidemiological Approaches to the Identification of Cancer Predisposition Genes -- Characterization of Translocations in Human Cancer -- Positional Approaches to Cancer Genetics -- Hybrid Capture of Putative Tumor Suppressor Genes -- Approaches to Proteomic Analysis of Human Tumors -- Representational Difference Analysis of Gene Expression -- Antisense Libraries to Isolate Tumor Suppressor Genes -- Genetic Suppressor Elements in the Characterization and Identification of Tumor Suppressor Genes -- Cross-linking Subtractive Hybridization to Identify Tumor Suppressor Genes -- Suppression Subtractive Hybridization for Identification and Functional Analysis of Tumor Suppressor Genes -- SAGE as a Strategy to Isolate Cancer-Related Genes -- Differential Display Techniques to Identify Tumor Suppressor Gene Pathways -- Detection of Mismatch Repair Gene Expression in Urologic Malignancies.<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\nschema:description<\/a> \"Powerful new tools are now available to discover and understand tumor suppressor genes (TSGs) and the biochemical mechanisms by which they control cancer development and progression. In Tumor Suppressor Genes, Volume 1: Pathways and Isolation Strategies, leading physician scientists and academic researchers review all the known tumor suppressor genes, explain how they work, and describe how they were discovered and isolated. In many cases, the authors discuss specific genes that are frequently involved in hereditary or sporadic cancers. They also provide a detailed guide to using powerful molecular genetic, cytogenetic, proteomic, and cell biological strategies to isolate and characterize novel tumor suppressor genes and their targets. The companion volume of this set, Tumor Suppressor Genes, Volume 2: Regulation, Function, and Medicinal Applications, demonstrates how best to explore the cell biology and biochemical function of such genes, and their encoded proteins, to study their physiological role in vivo, and to use information on TSGs to develop diagnostic and therapeutic strategies for cancer. Comprehensive and authoritative, the two volumes of Tumor Suppressor Genes provide an unparalleled compilation of key data on all known tumor suppressor pathways and a treasury of techniques for their discovery, analysis, and uses in cancer therapeutics.<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\nschema:exampleOfWork<\/a> <http:\/\/worldcat.org\/entity\/work\/id\/2796866662<\/a>> ;\u00A0\u00A0\u00A0\nschema:genre<\/a> \"Laboratory manuals<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\nschema:genre<\/a> \"Electronic books<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\nschema:inLanguage<\/a> \"en<\/span>\" ;\u00A0\u00A0\u00A0\nschema:isPartOf<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/2796866662#Series\/methods_in_molecular_biology_clifton_n_j<\/a>> ; # Methods in molecular biology (Clifton, N.J.) ;<\/span>\n\u00A0\u00A0\u00A0\nschema:isPartOf<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/2796866662#Series\/methods_in_molecular_biology<\/a>> ; # Methods in molecular biology ;<\/span>\n\u00A0\u00A0\u00A0\nschema:isSimilarTo<\/a> <http:\/\/www.worldcat.org\/oclc\/52288595<\/a>> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Tumor suppressor genes. Volume 1, Pathways and isolation strategies<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\nschema:productID<\/a> \"170622033<\/span>\" ;\u00A0\u00A0\u00A0\nschema:publication<\/a> <http:\/\/www.worldcat.org\/title\/-\/oclc\/170622033#PublicationEvent\/totowa_n_j_great_britain_humana_press_2003<\/a>> ;\u00A0\u00A0\u00A0\nschema:publisher<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/2796866662#Agent\/humana_press<\/a>> ; # Humana Press<\/span>\n\u00A0\u00A0\u00A0\nschema:url<\/a> <http:\/\/www.myilibrary.com?id=84212<\/a>> ;\u00A0\u00A0\u00A0\nschema:url<\/a> <http:\/\/link.springer.com\/book\/10.1385\/1592593283<\/a>> ;\u00A0\u00A0\u00A0\nschema:url<\/a> <https:\/\/0-link-springer-com.pugwash.lib.warwick.ac.uk\/book\/10.1385\/1592593283<\/a>> ;\u00A0\u00A0\u00A0\nschema:url<\/a> <http:\/\/www.library.yorku.ca\/e\/resolver\/id\/2479120<\/a>> ;\u00A0\u00A0\u00A0\nschema:url<\/a> <https:\/\/search.ebscohost.com\/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=201397<\/a>> ;\u00A0\u00A0\u00A0\nschema:url<\/a> <https:\/\/doi.org\/10.1385\/1592593283<\/a>> ;\u00A0\u00A0\u00A0\nschema:url<\/a> <http:\/\/link.springer.com\/10.1385\/1592593283<\/a>> ;\u00A0\u00A0\u00A0\nschema:url<\/a> <https:\/\/link.springer.com\/openurl?genre=book&isbn=978-0-89603-986-5<\/a>> ;\u00A0\u00A0\u00A0\nschema:workExample<\/a> <http:\/\/worldcat.org\/isbn\/9780896039865<\/a>> ;\u00A0\u00A0\u00A0\nschema:workExample<\/a> <http:\/\/dx.doi.org\/10.1385\/1592593283<\/a>> ;\u00A0\u00A0\u00A0\nschema:workExample<\/a> <http:\/\/worldcat.org\/isbn\/9781592593286<\/a>> ;\u00A0\u00A0\u00A0\nwdrs:describedby<\/a> <http:\/\/www.worldcat.org\/title\/-\/oclc\/170622033<\/a>> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n\n

Related Entities<\/h3>\n
<http:\/\/dewey.info\/class\/616.994042\/e22\/<\/a>>\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/dx.doi.org\/10.1385\/1592593283<\/a>>\u00A0\u00A0\u00A0\u00A0a \nschema:IndividualProduct<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/2796866662#Agent\/humana_press<\/a>> # Humana Press<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nbgn:Agent<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Humana Press<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/2796866662#Place\/great_britain<\/a>> # Great Britain<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Place<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Great Britain<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/2796866662#Place\/totowa_n_j<\/a>> # Totowa, N.J.<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Place<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Totowa, N.J.<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/2796866662#Series\/methods_in_molecular_biology<\/a>> # Methods in molecular biology ;<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nbgn:PublicationSeries<\/a> ;\u00A0\u00A0\u00A0\nschema:hasPart<\/a> <http:\/\/www.worldcat.org\/oclc\/170622033<\/a>> ; # Tumor suppressor genes. Volume 1, Pathways and isolation strategies<\/span>\n\u00A0\u00A0\u00A0\nschema:name<\/a> \"Methods in molecular biology ;<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/2796866662#Series\/methods_in_molecular_biology_clifton_n_j<\/a>> # Methods in molecular biology (Clifton, N.J.) ;<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nbgn:PublicationSeries<\/a> ;\u00A0\u00A0\u00A0\nschema:hasPart<\/a> <http:\/\/www.worldcat.org\/oclc\/170622033<\/a>> ; # Tumor suppressor genes. Volume 1, Pathways and isolation strategies<\/span>\n\u00A0\u00A0\u00A0\nschema:name<\/a> \"Methods in molecular biology (Clifton, N.J.) ;<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/2796866662#Topic\/antioncogenes<\/a>> # Antioncogenes<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Antioncogenes<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/2796866662#Topic\/genes_tumor_suppressor<\/a>> # Genes, Tumor Suppressor<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Genes, Tumor Suppressor<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/2796866662#Topic\/health_&_fitness_diseases_cancer<\/a>> # HEALTH & FITNESS--Diseases--Cancer<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"HEALTH & FITNESS--Diseases--Cancer<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/experiment.worldcat.org\/entity\/work\/data\/2796866662#Topic\/medical_oncology<\/a>> # MEDICAL--Oncology<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"MEDICAL--Oncology<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Medical Oncology<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/id.loc.gov\/authorities\/subjects\/sh90002154<\/a>> # Antioncogenes<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Intangible<\/a> ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Antioncogenes<\/span>\"@en<\/a> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/id.loc.gov\/vocabulary\/countries\/nju<\/a>>\u00A0\u00A0\u00A0\u00A0a \nschema:Place<\/a> ;\u00A0\u00A0\u00A0\ndcterms:identifier<\/a> \"nju<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/viaf.org\/viaf\/74109351<\/a>> # Wafik S. El-Deiry<\/span>\n\u00A0\u00A0\u00A0\u00A0a \nschema:Person<\/a> ;\u00A0\u00A0\u00A0\nschema:familyName<\/a> \"El-Deiry<\/span>\" ;\u00A0\u00A0\u00A0\nschema:givenName<\/a> \"Wafik S.<\/span>\" ;\u00A0\u00A0\u00A0\nschema:name<\/a> \"Wafik S. El-Deiry<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/worldcat.org\/isbn\/9780896039865<\/a>>\u00A0\u00A0\u00A0\u00A0a \nschema:ProductModel<\/a> ;\u00A0\u00A0\u00A0\nschema:isbn<\/a> \"0896039862<\/span>\" ;\u00A0\u00A0\u00A0\nschema:isbn<\/a> \"9780896039865<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/worldcat.org\/isbn\/9781592593286<\/a>>\u00A0\u00A0\u00A0\u00A0a \nschema:ProductModel<\/a> ;\u00A0\u00A0\u00A0\nschema:isbn<\/a> \"1592593283<\/span>\" ;\u00A0\u00A0\u00A0\nschema:isbn<\/a> \"9781592593286<\/span>\" ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/www.worldcat.org\/oclc\/52288595<\/a>>\u00A0\u00A0\u00A0\u00A0a \nschema:CreativeWork<\/a> ;\u00A0\u00A0\u00A0\nrdfs:label<\/a> \"Tumor suppressor genes. Volume 1, Pathways and isolation strategies.<\/span>\" ;\u00A0\u00A0\u00A0\nschema:description<\/a> \"Print version:<\/span>\" ;\u00A0\u00A0\u00A0\nschema:isSimilarTo<\/a> <http:\/\/www.worldcat.org\/oclc\/170622033<\/a>> ; # Tumor suppressor genes. Volume 1, Pathways and isolation strategies<\/span>\n\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/www.worldcat.org\/title\/-\/oclc\/170622033<\/a>>\u00A0\u00A0\u00A0\u00A0a \ngenont:InformationResource<\/a>, genont:ContentTypeGenericResource<\/a> ;\u00A0\u00A0\u00A0\nschema:about<\/a> <http:\/\/www.worldcat.org\/oclc\/170622033<\/a>> ; # Tumor suppressor genes. Volume 1, Pathways and isolation strategies<\/span>\n\u00A0\u00A0\u00A0\nschema:dateModified<\/a> \"2020-03-28<\/span>\" ;\u00A0\u00A0\u00A0\nvoid:inDataset<\/a> <http:\/\/purl.oclc.org\/dataset\/WorldCat<\/a>> ;\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n
<http:\/\/www.worldcat.org\/title\/-\/oclc\/170622033#PublicationEvent\/totowa_n_j_great_britain_humana_press_2003<\/a>>\u00A0\u00A0\u00A0\u00A0a \nschema:PublicationEvent<\/a> ;\u00A0\u00A0\u00A0\nschema:location<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/2796866662#Place\/great_britain<\/a>> ; # Great Britain<\/span>\n\u00A0\u00A0\u00A0\nschema:location<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/2796866662#Place\/totowa_n_j<\/a>> ; # Totowa, N.J.<\/span>\n\u00A0\u00A0\u00A0\nschema:organizer<\/a> <http:\/\/experiment.worldcat.org\/entity\/work\/data\/2796866662#Agent\/humana_press<\/a>> ; # Humana Press<\/span>\n\u00A0\u00A0\u00A0\u00A0.\n\n\n<\/div>\n